G4RJZ1 · CAS7_THETK
- ProteinCRISPR-associated protein Cas7/Cst2/DevR
- Genecas7
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids329 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Biological Process | defense response to virus |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCRISPR-associated protein Cas7/Cst2/DevR
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Thermoproteales > Thermoproteaceae > Thermoproteus
Accessions
- Primary accessionG4RJZ1
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000422236 | 1-329 | CRISPR-associated protein Cas7/Cst2/DevR | |||
Sequence: MRVAPPYVRAAGRFEAQLSVLTGAGNMGNYNMHAVAKVIHGGKAYEVPVLTGNALKHWHSVYLAEVYQDLGGTQLNEFCKKGVGLRGKNMSGEDASSEAEAIKDLCNDLHGFLLPDKQIKRDSLVRVSFAVPVLEEKNLEAASKFAVVHNRVDPFKRTQQVKSKEEQEGTEMMVFKQEYSSAVYGFAAAMDLGLSGVPLYQEGESGVDDRERALRIKSALVALLRLFNGVGSKQARALPIARLRELVIAISDSPIPNLVHGAYPDYVARSAELLTAYLKAVGKKGVVLCYGVDCPQSNNVLECKKADTLDDLFQEALRRALPGGQPARR |
Proteomic databases
Expression
Induction
Repressed by 5 J/m2 ultraviolet light and 50 mM NaCl, slightly induced by 20 J/m2 ultraviolet light, 100 and 150 mM Nacl. Member of the csa5-cas7-cas5a-cas3-cas3'-cas8a2 operon.
Interaction
Subunit
Can form a Cascade complex with Csa5, Cas5a, Cas3, Cas3' and Cas8a2.
Protein-protein interaction databases
Structure
Family & Domains
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length329
- Mass (Da)35,903
- Last updated2011-12-14 v1
- Checksum8A4143EB24970CB7
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN869859 EMBL· GenBank· DDBJ | CCC81886.1 EMBL· GenBank· DDBJ | Genomic DNA |