G3GDE0 · G3GDE0_BOMVA
- ProteinCytochrome b
- Genecytb
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids365 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 heme groups non-covalently.
Note: Binds 2 heme groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 69 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 83 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 168 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 182 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 187 | a ubiquinone (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | respiratory electron transport chain |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Gene names
Encoded on
- Mitochondrion
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Bombinatoridae > Bombina
Accessions
- Primary accessionG3GDE0
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 15-38 | Helical | ||||
Sequence: AWWNFGSLLGICLIIQILTGLFLA | ||||||
Transmembrane | 73-93 | Helical | ||||
Sequence: ASFFFICIYFHIGRGIYYGSF | ||||||
Transmembrane | 99-119 | Helical | ||||
Sequence: WNIGVILLFLVMATAFVGYVL | ||||||
Transmembrane | 131-152 | Helical | ||||
Sequence: VITNLLSAVPYIGTTLVQWIWG | ||||||
Transmembrane | 164-186 | Helical | ||||
Sequence: FFAFHFLLPFVIAGATILHLLFL | ||||||
Transmembrane | 215-236 | Helical | ||||
Sequence: LLGFLLMLTMLALLAMFSPNLL | ||||||
Transmembrane | 274-293 | Helical | ||||
Sequence: LGGVLALVFSILILALLPLL | ||||||
Transmembrane | 305-326 | Helical | ||||
Sequence: PITQIIFWSLIADTLILTWIGG | ||||||
Transmembrane | 332-352 | Helical | ||||
Sequence: PFILIGQVASLIYFFIFLILL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-195 | Cytochrome b/b6 N-terminal region profile | ||||
Sequence: NGSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTADTTMAFSSVAHICRDVNYGWLIRNLHANGASFFFICIYFHIGRGIYYGSFLFKETWNIGVILLFLVMATAFVGYVLPWGQMSFWGATVITNLLSAVPYIGTTLVQWIWGGFSVDNATLTRFFAFHFLLPFVIAGATILHLLFLHETGSNNPT | ||||||
Domain | 196-365 | Cytochrome b/b6 C-terminal region profile | ||||
Sequence: GLNSNTDKIPFHPYFSYKDLLGFLLMLTMLALLAMFSPNLLGDPDNFAPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILALLPLLHTAKQRSMMFRPITQIIFWSLIADTLILTWIGGQPVEEPFILIGQVASLIYFFIFLILLPASGWLENKMLSW |
Sequence similarities
Belongs to the cytochrome b family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length365
- Mass (Da)40,965
- Last updated2011-11-16 v1
- ChecksumEA3E5C2B78BE6E15
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: N | ||||||
Non-terminal residue | 365 | |||||
Sequence: W |