F2X0X3 · F2X0X3_PTYFL
- ProteinFrizzled receptor 1/2/7
- Genefz1/2/7
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids552 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | Wnt receptor activity | |
Molecular Function | Wnt-protein binding | |
Biological Process | canonical Wnt signaling pathway | |
Biological Process | non-canonical Wnt signaling pathway |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Hemichordata > Enteropneusta > Ptychoderidae > Ptychodera
Accessions
- Primary accessionF2X0X3
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 226-248 | Helical | ||||
Sequence: IWIGIWSILCAASTLFTVSTFLI | ||||||
Transmembrane | 260-283 | Helical | ||||
Sequence: IIFYLRVIFMVSLTYVVGFIAYII | ||||||
Transmembrane | 312-333 | Helical | ||||
Sequence: ILFMILYFFSMASSIWWVILSL | ||||||
Transmembrane | 354-373 | Helical | ||||
Sequence: YFHLAAWSVPAVKTIAILAM | ||||||
Transmembrane | 403-424 | Helical | ||||
Sequence: LFLYLLIGTSFLLAGFVALYRI | ||||||
Transmembrane | 445-466 | Helical | ||||
Sequence: IGIFSVLYTVPATIVIACFFYE | ||||||
Transmembrane | 505-527 | Helical | ||||
Sequence: FTVFMIKYLMLLIVGITSGFWIW |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-25 | |||||
Sequence: MAERKGTNLLWISAFMVNLLNVVVC | ||||||
Chain | PRO_5003292693 | 26-552 | ||||
Sequence: QQQYDSLSGVLPHHGRCEPISIPLCQDIAYNETIMPNLLNHQKQDEAGLEVHQFFPLVKVECSVDLKFFLCAVYAPVCTVLETPLPPCRSLCQSAKNGCEALMNRFGFQWPERLDCNTFPVHGSGPLCVGQNRSVPTAMPTTKPDNKSVTPSSDTVVPPFTCPDELRVPAYLDYNFLDADACGAPCDSMFFSETQREFARIWIGIWSILCAASTLFTVSTFLIDMPRFRYPERPIIFYLRVIFMVSLTYVVGFIAYIIDTEIACNGPYEEGRWSIAVQGTKKEGCTILFMILYFFSMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWSVPAVKTIAILAMSEVDGDVLAGVCFVGFTNVDALRGFVLAPLFLYLLIGTSFLLAGFVALYRIRTFMKHDGTKTDKLEKLMIRIGIFSVLYTVPATIVIACFFYEQANRQLWEYSWMVNNCKKLHFSCPHGTGPTPMGLATPDFTVFMIKYLMLLIVGITSGFWIWSGKTLNSWRKFYMRLVHHRRDETTV | ||||||
Disulfide bond | 42↔103 | |||||
Sequence: CEPISIPLCQDIAYNETIMPNLLNHQKQDEAGLEVHQFFPLVKVECSVDLKFFLCAVYAPVC | ||||||
Disulfide bond | 50↔96 | |||||
Sequence: CQDIAYNETIMPNLLNHQKQDEAGLEVHQFFPLVKVECSVDLKFFLC | ||||||
Disulfide bond | 117↔141 | |||||
Sequence: CQSAKNGCEALMNRFGFQWPERLDC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 37-156 | FZ | ||||
Sequence: PHHGRCEPISIPLCQDIAYNETIMPNLLNHQKQDEAGLEVHQFFPLVKVECSVDLKFFLCAVYAPVCTVLETPLPPCRSLCQSAKNGCEALMNRFGFQWPERLDCNTFPVHGSGPLCVGQ | ||||||
Domain | 228-534 | G-protein coupled receptors family 2 profile 2 | ||||
Sequence: IGIWSILCAASTLFTVSTFLIDMPRFRYPERPIIFYLRVIFMVSLTYVVGFIAYIIDTEIACNGPYEEGRWSIAVQGTKKEGCTILFMILYFFSMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWSVPAVKTIAILAMSEVDGDVLAGVCFVGFTNVDALRGFVLAPLFLYLLIGTSFLLAGFVALYRIRTFMKHDGTKTDKLEKLMIRIGIFSVLYTVPATIVIACFFYEQANRQLWEYSWMVNNCKKLHFSCPHGTGPTPMGLATPDFTVFMIKYLMLLIVGITSGFWIWSGKTLNS |
Sequence similarities
Belongs to the G-protein coupled receptor Fz/Smo family.
Keywords
- Domain
Family and domain databases
Protein family/group databases
Sequence
- Sequence statusComplete
- Length552
- Mass (Da)62,441
- Last updated2011-05-31 v1
- Checksum5EB8212E32336E2E