D5Q3T4 · D5Q3T4_CLODI
- ProteinN-acetyl-gamma-glutamyl-phosphate reductase
- GeneargC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids344 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
Catalytic activity
- N-acetyl-L-glutamate 5-semialdehyde + phosphate + NADP+ = N-acetyl-L-glutamyl 5-phosphate + NADPH + H+
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 3/4.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 150 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | N-acetyl-gamma-glutamyl-phosphate reductase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP+ binding | |
Biological Process | arginine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameN-acetyl-gamma-glutamyl-phosphate reductase
- EC number
- Short namesAGPR
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Peptostreptococcales > Peptostreptococcaceae > Clostridioides
Accessions
- Primary accessionD5Q3T4
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 5-142 | Semialdehyde dehydrogenase NAD-binding | ||||
Sequence: KVGIIGATGYVGAELIRLLINHDKAELTAIGSNSYVGKDIVDIYPSIGYKNNMICIENEKVIDVCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADFRIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKDDIKDA |
Sequence similarities
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length344
- Mass (Da)38,136
- Last updated2010-07-13 v1
- Checksum6099DB66445A718C