D5ANZ3 · CYB_RHOCB

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.

Miscellaneous

Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme b groups non-covalently.

Features

Showing features for binding site.

143750100150200250300350400
TypeIDPosition(s)Description
Binding site97Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site111Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site198Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site212Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processrespiratory electron transport chain

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      petB
    • Synonyms
      cytB
    • Ordered locus names
      RCAP_rcc02769

Organism names

Accessions

  • Primary accession
    D5ANZ3
  • Secondary accessions
    • P07057
    • P08502

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane45-65Helical
Transmembrane100-120Helical
Transmembrane129-149Helical
Transmembrane156-176Helical
Transmembrane194-214Helical
Transmembrane248-268Helical
Transmembrane298-318Helical
Transmembrane330-350Helical
Transmembrane365-385Helical
Transmembrane391-411Helical

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis144Loss of binding affinity for ubiquinone and ubiquinol.

PTM/Processing

Features

Showing features for initiator methionine, chain.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00004098642-437Cytochrome b

Interaction

Subunit

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    437
  • Mass (Da)
    49,350
  • Last updated
    2010-06-15 v1
  • Checksum
    F1A21D35DCE8C7A8
MSGIPHDHYEPKTGIEKWLHDRLPIVGLVYDTIMIPTPKNLNWWWIWGIVLAFTLVLQIVTGIVLAMHYTPHVDLAFASVEHIMRDVNGGWAMRYIHANGASLFFLAVYIHIFRGLYYGSYKAPREITWIVGMVIYLLMMGTAFMGYVLPWGQMSFWGATVITGLFGAIPGIGPSIQAWLLGGPAVDNATLNRFFSLHYLLPFVIAALVAIHIWAFHTTGNNNPTGVEVRRTSKADAEKDTLPFWPYFVIKDLFALALVLLGFFAVVAYMPNYLGHPDNYVQANPLSTPAHIVPEWYFLPFYAILRAFAADVWVVILVDGLTFGIVDAKFFGVIAMFGAIAVMALAPWLDTSKVRSGAYRPKFRMWFWFLVLDFVVLTWVGAMPTEYPYDWISLIASTYWFAYFLVILPLLGATEKPEPIPASIEEDFNSHYGNPAE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X05630
EMBL· GenBank· DDBJ
CAA29117.1
EMBL· GenBank· DDBJ
Genomic DNA
CP001312
EMBL· GenBank· DDBJ
ADE86498.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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