D3DJR9 · D3DJR9_HYDTT
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- GeneaccD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids280 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- N6-carboxybiotinyl-L-lysyl-[protein] + acetyl-CoA = N6-biotinyl-L-lysyl-[protein] + malonyl-CoA
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Aquificota > Aquificia > Aquificales > Aquificaceae > Hydrogenobacter
Accessions
- Primary accessionD3DJR9
Proteomes
Subcellular Location
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 18-280 | CoA carboxyltransferase N-terminal | ||||
Sequence: LWTKCPECKTILYIPELSANLKVCPKCNYHFPMNAKERVESLLDGDVEVLFENILPKDPLGFKDTKSYKDRIRQAQDETGMSEAILVVRGRLRDIPMVLTVMDFSFIGGSMGSVVGERFYRACKLSASQNLPLVSVITSGGARMQEGILSLMQMAKTSIGVGLLEEKGLPYITVLTDPTMGGVSASFAFLGDIILAEPRSLIGFAGPRVIEQTIKQQLPEGFQRSEFLLEKGMLDMVVHRKELKDVLYRLLKMSTHGGRYVGI | ||||||
Zinc finger | 22-44 | C4-type | ||||
Sequence: CPECKTILYIPELSANLKVCPKC |
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length280
- Mass (Da)31,334
- Last updated2010-03-23 v1
- ChecksumC9422D277E6856AB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP011112 EMBL· GenBank· DDBJ | BAI70071.1 EMBL· GenBank· DDBJ | Genomic DNA |