D2IFJ8 · D2IFJ8_9PETR
- ProteinCytochrome b
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids377 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 heme groups non-covalently.
Note: Binds 2 heme groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 87 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 101 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 186 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 200 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 205 | a ubiquinone (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | mitochondrial electron transport, ubiquinol to cytochrome c |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Encoded on
- Mitochondrion
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Cyclostomata > Hyperoartia > Petromyzontiformes > Petromyzontidae > Ichthyomyzon
Accessions
- Primary accessionD2IFJ8
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 34-60 | Helical | ||||
Sequence: WWNFGSLLSLCLIIQIITGLILAMHYT | ||||||
Transmembrane | 81-102 | Helical | ||||
Sequence: WLMRNLHANGASMFFICIYAHI | ||||||
Transmembrane | 117-137 | Helical | ||||
Sequence: WNIGVILFTLTAATAFVGYVL | ||||||
Transmembrane | 182-204 | Helical | ||||
Sequence: FFTFHFILPFILTAMTMIHIMFL | ||||||
Transmembrane | 233-250 | Helical | ||||
Sequence: ILGFVILLSILFMISLLA | ||||||
Transmembrane | 292-311 | Helical | ||||
Sequence: LGGVLALVMAIMILLIIPLT | ||||||
Transmembrane | 323-342 | Helical | ||||
Sequence: PLAQTMFWILIANLVLLTWL | ||||||
Transmembrane | 354-373 | Helical | ||||
Sequence: MTQIASTVYFLIFILVFPTL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-213 | Cytochrome b/b6 N-terminal region profile | ||||
Sequence: LPSIIRKNNPLLSLGNNMLVDLPSPANISAWWNFGSLLSLCLIIQIITGLILAMHYTANTELAFSSVMHICRDVNNGWLMRNLHANGASMFFICIYAHIGRGIYYGSYLYKETWNIGVILFTLTAATAFVGYVLPWGQMSFWGATVITNLISATPYVGDDIVVWLWGGFSVSNATLTRFFTFHFILPFILTAMTMIHIMFLHQTGSSNPM | ||||||
Domain | 214-377 | Cytochrome b/b6 C-terminal region profile | ||||
Sequence: GVNSNLDKIQFHPYFSFKDILGFVILLSILFMISLLAPNTLGEPDNFIFANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMAIMILLIIPLTHTSKQRSMQFRPLAQTMFWILIANLVLLTWLGGEPAEYPFTSMTQIASTVYFLIFILVFPTLGHLE |
Sequence similarities
Belongs to the cytochrome b family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length377
- Mass (Da)42,393
- Last updated2010-02-09 v1
- Checksum42F7EBD00854D4EF
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 377 | |||||
Sequence: E |