D0KRN0 · D0KRN0_SACS9

Function

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.

Features

Showing features for active site, binding site.

133650100150200250300
TypeIDPosition(s)Description
Active site202Schiff-base intermediate with substrate
Binding site2125-aminolevulinate 1 (UniProtKB | ChEBI)
Binding site2245-aminolevulinate 1 (UniProtKB | ChEBI)
Binding site240Mg2+ (UniProtKB | ChEBI)
Active site255Schiff-base intermediate with substrate
Binding site2825-aminolevulinate 2 (UniProtKB | ChEBI)
Binding site3215-aminolevulinate 2 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionmetal ion binding
Molecular Functionporphobilinogen synthase activity
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Delta-aminolevulinic acid dehydratase
  • EC number

Gene names

    • Ordered locus names
      Ssol_1161

Organism names

Accessions

  • Primary accession
    D0KRN0

Interaction

Subunit

Homooctamer.

Family & Domains

Sequence similarities

Belongs to the ALAD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    336
  • Mass (Da)
    37,630
  • Last updated
    2009-12-15 v1
  • Checksum
    3F88B5B7B5A81196
MVTFPVLRPRRLRKSKLVRDLVSETSISQNDLVLPVFIKENINEPEQIASMPGIYRYPPNDKLINYLQDSYENGIRSVILFGIPSYKDDIASSAYDKNGIIQRAVRIIKDSFKDKIIVITDECTDEYMANGHCGLVKYTNGCYVVDNDESLKIHAKIALSQAEAGADVIAPSSMMDGVVRAIRDALDSAGYIDTLILSYSVKYASVMYGPFRDAAYSKPAFGDRRGYQMDPRNAFEAIKEARLDIEEGADILMVKPAHTYLDVIRLVKDHFPEYPLAAYHVSGEYSMIKAAAINGWIDEKTAVLEITTAIKRAGADLIITYYANDIARWIKDGVPF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001800
EMBL· GenBank· DDBJ
ACX91399.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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