C9REY1 · BIOW_METVM
- Protein6-carboxyhexanoate--CoA ligase
- GenebioW
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids233 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
Catalytic activity
- heptanedioate + ATP + CoA = 6-carboxyhexanoyl-CoA + AMP + diphosphate
Cofactor
Pathway
Metabolic intermediate metabolism; pimeloyl-CoA biosynthesis; pimeloyl-CoA from pimelate: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 6-carboxyhexanoate-CoA ligase activity | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Biological Process | biotin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name6-carboxyhexanoate--CoA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Methanomada group > Methanococci > Methanococcales > Methanocaldococcaceae > Methanocaldococcus
Accessions
- Primary accessionC9REY1
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000412097 | 1-233 | 6-carboxyhexanoate--CoA ligase | |||
Sequence: MYSIKMRASKNGKHISGAERIVEKEKIEEVVKDLTKRALNHENGTPDFINIKVEKIVGEIEYIDHLPIITIPCKNIKEARKKAIEILINEGIPKEIILQAFEIIDRGGMRGAALLNLKGERLDPDKERGVRVKNIDVSESLKNEILTKNLGTERTVDAIAIASKVIHLGVLAELCTSDNKNYTTGYVATKKGYFRITNLKREGDPGGRVFFIKDDRNIKKLIEKLENKPCIIR |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length233
- Mass (Da)26,314
- Last updated2009-11-24 v1
- ChecksumE027E402ED275CD1
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001787 EMBL· GenBank· DDBJ | ACX72133.1 EMBL· GenBank· DDBJ | Genomic DNA |