C7UDU4 · CSN2_ENTFL

Function

function

CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
Binds dsDNA, binding is disrupted by EGTA

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Features

Showing features for binding site.

121920406080100120140160180200
TypeIDPosition(s)Description
Binding site118Ca2+ 1 (UniProtKB | ChEBI)
Binding site118Ca2+ 2 (UniProtKB | ChEBI)
Binding site122Ca2+ 1 (UniProtKB | ChEBI)
Binding site122Ca2+ 3 (UniProtKB | ChEBI)
Binding site123Ca2+ 1 (UniProtKB | ChEBI)
Binding site123Ca2+ 3 (UniProtKB | ChEBI)
Binding site128Ca2+ 1 (UniProtKB | ChEBI)
Binding site128Ca2+ 3 (UniProtKB | ChEBI)
Binding site132Ca2+ 3 (UniProtKB | ChEBI)
Binding site132Ca2+ 4 (UniProtKB | ChEBI)
Binding site138Ca2+ 2 (UniProtKB | ChEBI)
Binding site138Ca2+ 4 (UniProtKB | ChEBI)
Binding site142Ca2+ 2 (UniProtKB | ChEBI)
Binding site142Ca2+ 4 (UniProtKB | ChEBI)
Binding site150Ca2+ 2 (UniProtKB | ChEBI)
Binding site150Ca2+ 4 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionDNA binding
Molecular Functionmetal ion binding
Biological Processdefense response to virus

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    CRISPR-associated protein Csn2

Gene names

    • Name
      csn2
    • ORF names
      EFDG_01320

Organism names

Accessions

  • Primary accession
    C7UDU4

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004183411-219CRISPR-associated protein Csn2

Interaction

Subunit

Homotetramer.

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    219
  • Mass (Da)
    25,407
  • Last updated
    2009-10-13 v1
  • Checksum
    805E67157A12B6D3
MRVNFSLLEEPIEIEKATFLTIKDVQSFAHLVKLIYQYDGENELKLFDAQQKGLKPTELFVVTDILGYDVNSAATLKLIYGDLEAQLNDKPEVKSMIEKLTGTISQLIGYELLEHEMDLEEDGIIVQELFKALGIKIETTSDTIFEKVMEITQVHRYLSKKKLLIFINACTYLTEDEVQQVVEYISLNNVDVLFLEQRVVQNRFQYILDENFYLSYEKA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG670377
EMBL· GenBank· DDBJ
EEU16261.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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