C7P7L7 · HPRT_METFA

Function

function

Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionguanine phosphoribosyltransferase activity
Molecular Functionhypoxanthine phosphoribosyltransferase activity
Biological Processhypoxanthine salvage
Biological ProcessIMP salvage
Biological Processpurine ribonucleoside salvage

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Hypoxanthine/guanine phosphoribosyltransferase
  • EC number
  • Short names
    HGPRTase

Gene names

    • Name
      hpt
    • Ordered locus names
      Mefer_0731

Organism names

Accessions

  • Primary accession
    C7P7L7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004154661-183Hypoxanthine/guanine phosphoribosyltransferase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    183
  • Mass (Da)
    20,299
  • Last updated
    2009-10-13 v1
  • Checksum
    E4C4168609D762AD
MLLEETLKSCPIVKRGEYHYFIHPISDGVPVVDPKLLREVVTRIIKIGNFEDVDKIVTAEAMGIPLVTTLSLYTDIPYVIMRKREYKLPGEIPVFQSTGYSKGQLYLNGIEKGDKVVIIDDVISTGGTLIAIIEALKKAGAEIKDIICVIERGEGKKIVEEKTGYKIKTLVKIDVVDGKVVIL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001696
EMBL· GenBank· DDBJ
ACV24549.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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