C6A2E4 · G1PDH_THESM

Function

function

Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site97-101NAD+ (UniProtKB | ChEBI)
Binding site119-122NAD+ (UniProtKB | ChEBI)
Binding site124substrate
Binding site128NAD+ (UniProtKB | ChEBI)
Binding site171substrate
Binding site171Zn2+ (UniProtKB | ChEBI); catalytic
Binding site251Zn2+ (UniProtKB | ChEBI); catalytic
Binding site255substrate
Binding site267Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionglycerol-1-phosphate dehydrogenase (NAD+) activity
Molecular Functionglycerol-1-phosphate dehydrogenase (NADP+) activity
Molecular Functionmetal ion binding
Biological Processglycerophospholipid metabolic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-1-phosphate dehydrogenase [NAD(P)+]
  • EC number
  • Short names
    G1P dehydrogenase
    ; G1PDH
  • Alternative names
    • Enantiomeric glycerophosphate synthase
    • sn-glycerol-1-phosphate dehydrogenase

Gene names

    • Name
      egsA
    • Ordered locus names
      TSIB_0726

Organism names

Accessions

  • Primary accession
    C6A2E4

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10002064821-350Glycerol-1-phosphate dehydrogenase [NAD(P)+]

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the glycerol-1-phosphate dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    350
  • Mass (Da)
    38,069
  • Last updated
    2009-09-01 v1
  • Checksum
    74DD6AA862A25B71
MVMFMHLMELPREVLLGEDLKDKVSQVAKRLKLGENVLILYGPKTKEIAGKDIEKHLKEFFHVKNLLIKEASMKNVQKALEIIRNENIDWLLGVGGGSIIDVAKLASFKADVPFISFPTTASHDGIASANASIRDLGAKTSIKARPPVAVIADVNIIKTAPYRYLAAGVGDMVSNLTAVKDWELAHRIRGEYFSEYAASLSLMSAKMVIKNADIIRLSNEESVRKVIKALISSGVAMSIAGSSRPASGAEHLFSHALDAIAPKPALHGEQCGVGTIIMAYLHGLNWKKIRETLKRVGAPTNAYELEIDPGFIIEALTIAHTIRPERYTILGKDGLTKEAAEKAAKITGVI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001463
EMBL· GenBank· DDBJ
ACS89789.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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