C5P8M7 · STS1_COCP7

Function

function

Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnuclear membrane
Molecular Functionproteasome binding
Biological Processnuclear protein quality control by the ubiquitin-proteasome system
Biological Processproteasome localization
Biological Processprotein transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Tethering factor for nuclear proteasome STS1

Gene names

    • Name
      STS1
    • ORF names
      CPC735_002580

Organism names

Accessions

  • Primary accession
    C5P8M7

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004094071-314Tethering factor for nuclear proteasome STS1

Interaction

Subunit

Binds the proteasome.

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region24-85Disordered
Compositional bias35-49Basic and acidic residues
Compositional bias50-65Polar residues

Sequence similarities

Belongs to the cut8/STS1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    314
  • Mass (Da)
    34,490
  • Last updated
    2009-09-01 v1
  • Checksum
    AED1F5736E084A26
MNSLVATPPIPPHFYEHNRFNTTSRFVSPMNPAGSRKRKAEDDNGSSDHDTRMSASPTSSPALPTKPLAARQIKRPRPNLSGRPLSLGRLFETLDSDALRSVLRSLCDRHPELGQEVVDTAPRPNITSALQVLSNYQSTLQSSFPLGGNPSSDYAYNRVRPHVMNLLDALNDFTPHFLPPNETHPSTSLNYLDGVTEIIHQLPRWDTPHYNLEKEAAYEEIAKAWALVIREASKRGGGIQLQYGEWDQKLAKHNQTSGGKLQDAVHELSASLGWMAGNPSHPGPGCPQADTASIRQQLLSGTYGAGLPLKVGPW

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias35-49Basic and acidic residues
Compositional bias50-65Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACFW01000030
EMBL· GenBank· DDBJ
EER26089.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp