C5DCA2 · MTNB_LACTC

Function

function

Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site107substrate
Binding site125Zn2+ (UniProtKB | ChEBI)
Binding site127Zn2+ (UniProtKB | ChEBI)
Active site148Proton donor/acceptor
Binding site210Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmethylthioribulose 1-phosphate dehydratase activity
Molecular Functionzinc ion binding
Biological ProcessL-methionine salvage from methylthioadenosine
Biological ProcessL-methionine salvage from S-adenosylmethionine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylthioribulose-1-phosphate dehydratase
  • EC number
  • Short names
    MTRu-1-P dehydratase

Gene names

    • Name
      MDE1
    • Ordered locus names
      KLTH0B01386g

Organism names

Accessions

  • Primary accession
    C5DCA2

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003938271-257Methylthioribulose-1-phosphate dehydratase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the aldolase class II family. MtnB subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    257
  • Mass (Da)
    28,444
  • Last updated
    2009-07-28 v1
  • Checksum
    FACC1F6E0E7063CA
MASCFCNKVDVTEGTHGTSSSDDALVSSQDPRHPANLICTLCKMFYYNNWVTGTGGGISIKHSKTGHIYIAPSGVQKEQLKPADMFVMDPASGSYLRTPQLYKPSACTPLFMSCYKQRDAGAVIHTHSQHAVMCSLIFDKELRIANIEQIKAIPSGKKDAKTGKDINLSFFDTLVIPIIDNTAHEEDLTEGLQEALQKYPNTTAVIVRRHGIYVWGPSVDKAKVYNEAIDYLMEVAWKMHQLGIPPDCGIGEEKKYL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU928166
EMBL· GenBank· DDBJ
CAR21413.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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