B9KQX9 · COAX_CERSK

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Catalytic activity

Cofactor

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site107-110substrate
Active site109Proton acceptor
Binding site129K+ (UniProtKB | ChEBI)
Binding site132ATP (UniProtKB | ChEBI)
Binding site184substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • Ordered locus names
      RSKD131_0846

Organism names

Accessions

  • Primary accession
    B9KQX9

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001652061-257Type III pantothenate kinase

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    257
  • Mass (Da)
    28,076
  • Last updated
    2009-03-24 v1
  • Checksum
    E14EA33605A65547
MLLAIDCGNTNTVFSIWDGTQFLATWRIATDHKRTADEYHVWLSTLLSLTKIEARISEAVISSTVPRVVFNLRVLCNRYYDCRPLVVGKPECRLPVAPRVDQGTTVGPDRLVNTVAGFHLHGGNLIVVDFGTATTFDVVDADGAYIGGVIAPGVNLSLEALHMAAAALPHVDVTKPQQAIGTNTVACIQSGVYWGYIGLVEGIVRQIRLERDSPMKVIATGGLAPLFDQGFNLFDRVEDDLTMQGLVLIHQYNKDLE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001150
EMBL· GenBank· DDBJ
ACM00706.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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