B9KP36 · PUR9_CERSK

Function

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.
Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.

GO annotations

AspectTerm
Molecular FunctionIMP cyclohydrolase activity
Molecular Functionphosphoribosylaminoimidazolecarboxamide formyltransferase activity
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional purine biosynthesis protein PurH

Including 2 domains:

  • Recommended name
    Phosphoribosylaminoimidazolecarboxamide formyltransferase
  • EC number
  • Alternative names
    • AICAR transformylase
  • Recommended name
    IMP cyclohydrolase
  • EC number
  • Alternative names
    • ATIC
    • IMP synthase
    • Inosinicase

Gene names

    • Name
      purH
    • Ordered locus names
      RSKD131_2498

Organism names

Accessions

  • Primary accession
    B9KP36

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001229691-529Bifunctional purine biosynthesis protein PurH

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-149MGS-like

Domain

The IMP cyclohydrolase activity resides in the N-terminal region.

Sequence similarities

Belongs to the PurH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    529
  • Mass (Da)
    55,829
  • Last updated
    2009-03-24 v1
  • Checksum
    085069F91C150C9C
MTNLVPVGRALLSVSDKSGLLDLARALADLEVELISTGGTAAALRAAGLKVRDVAEVTGFPEMMDGRVKTLHPMVHGGLLALRDDDEHLVAMAAHGIEPIDLLVVNLYPFEAAVARGASYDDCIENIDIGGPAMIRAAAKNHRFVNVVTDTADYKALLDELRAHDGATRLSFRQKLALTAYARTAAYDTAVSTWMAGALKAEAPRRRSFAGTLAQTMRYGENPHQKAAFYTDGSARPGVATAKQWQGKELSYNNINDTDAAFELVAEFDPAEGPACVIVKHANPCGVARGATLAEAYARAFDCDRVSAFGGIIALNQPLDAATAEKITEIFTEVVIAPGADEEARAIFAAKKNLRLLTTEALPDPLAPGLAFKQVAGGFLVQDRDAGHVDALDLKVVTKRAPSDAELADLLFAWTVAKHVKSNAIVYVKDGATVGVGAGQMSRVDSTRIAARKSQDMAQALGLAQPLTQGSVVASDAFFPFADGLLAAAEAGATAIIQPGGSMRDDEVIAAADEAGLAMVFTGQRHFRH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001150
EMBL· GenBank· DDBJ
ACM02358.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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