B8B4D0 · SPX1_ORYSI
- ProteinSPX domain-containing protein 1
- GeneSPX1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids295 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Involved in plant adaptation to phosphate (Pi) starvation (By similarity).
Inhibits PHR2 DNA-binding activity via a Pi-dependent protein interaction (By similarity).
Suppresses the regulation on expression of PT2 by PHR2 and accumulation of shoot Pi (By similarity).
Optimizes growth under phosphate-limited conditions through a negative feedback loop of the PSI (phosphate starvation-induced) signaling pathway (By similarity).
Regulates the expression of SPX2, SPX3 and SPX5 (By similarity).
May be an important link between signal transduction pathways related to phosphate starvation and cold stress (By similarity).
Together with SPX2, plays a negative role in the regulation of leaf inclination by preventing RLI1 transcription factor activity in Pi depleted conditions (By similarity).
Inhibits PHR2 DNA-binding activity via a Pi-dependent protein interaction (By similarity).
Suppresses the regulation on expression of PT2 by PHR2 and accumulation of shoot Pi (By similarity).
Optimizes growth under phosphate-limited conditions through a negative feedback loop of the PSI (phosphate starvation-induced) signaling pathway (By similarity).
Regulates the expression of SPX2, SPX3 and SPX5 (By similarity).
May be an important link between signal transduction pathways related to phosphate starvation and cold stress (By similarity).
Together with SPX2, plays a negative role in the regulation of leaf inclination by preventing RLI1 transcription factor activity in Pi depleted conditions (By similarity).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Biological Process | cellular response to cold | |
Biological Process | cellular response to phosphate starvation | |
Biological Process | negative regulation of unidimensional cell growth | |
Biological Process | positive regulation of cellular response to phosphate starvation | |
Biological Process | regulation of leaf development |
Names & Taxonomy
Protein names
- Recommended nameSPX domain-containing protein 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa
Accessions
- Primary accessionB8B4D0
Proteomes
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000398346 | 1-295 | SPX domain-containing protein 1 | |||
Sequence: MKFGKSLSSQIVETLPEWRDKFLSYKDLKKRLKLIGGGGGGEERQAKRARVAADGGEEEAAAAAMTPEEAGFMRLLEAELDKFNSFFVEKEEEYIIRQKELQDRVARAAGRESKEELMRVRKEIVDFHGEMVLLENYSALNYTGLVKILKKYDKRTGALIRLPFIQKVLQQPFFTTDLLYKLVKQCEAMLDQLLPSNELPVSSEDGRGDSTNEDKPSNPSSSLVNGGTIPELDEIEYMESMYMKGTVAALRSLKEIRSGSSTVSAFSLPPLQGDSSPEEQQELWNKIPVIEQAAK |
Interaction
Subunit
Interacts (via SPX domain) with PHR2 (via C-terminus) (By similarity).
Interacts with RLI1 in the nucleus to prevents its positive regulation of leaf inclination during phosphate (Pi) starvation (By similarity).
Interacts with RLI1 in the nucleus to prevents its positive regulation of leaf inclination during phosphate (Pi) starvation (By similarity).
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-166 | SPX | ||||
Sequence: MKFGKSLSSQIVETLPEWRDKFLSYKDLKKRLKLIGGGGGGEERQAKRARVAADGGEEEAAAAAMTPEEAGFMRLLEAELDKFNSFFVEKEEEYIIRQKELQDRVARAAGRESKEELMRVRKEIVDFHGEMVLLENYSALNYTGLVKILKKYDKRTGALIRLPFIQ | ||||||
Region | 197-227 | Disordered | ||||
Sequence: NELPVSSEDGRGDSTNEDKPSNPSSSLVNGG | ||||||
Compositional bias | 213-227 | Polar residues | ||||
Sequence: EDKPSNPSSSLVNGG |
Domain
The SPX domain is sufficient for inhibition of PHR2 binding to DNA.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length295
- Mass (Da)33,122
- Last updated2009-03-03 v1
- ChecksumA90D7CBE631E0FD4
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 213-227 | Polar residues | ||||
Sequence: EDKPSNPSSSLVNGG |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM000131 EMBL· GenBank· DDBJ | EEC80929.1 EMBL· GenBank· DDBJ | Genomic DNA |