B7NL80 · TRHO_ECO7I

Function

function

Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-carboxymethoxyuridine (cmo5U) biosynthesis. May be part of an alternate pathway, which is able to bypass cmo5U biogenesis in a subset of tRNAs under aerobic conditions.

Catalytic activity

Features

Showing features for active site.

135050100150200250300350
TypeIDPosition(s)Description
Active site200Cysteine persulfide intermediate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA uridine(34) hydroxylase
  • EC number
  • Alternative names
    • tRNA hydroxylation protein O

Gene names

    • Name
      trhO
    • Synonyms
      yceA
    • Ordered locus names
      ECIAI39_2109

Organism names

Accessions

  • Primary accession
    B7NL80

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10002003591-350tRNA uridine34 hydroxylase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain146-240Rhodanese

Sequence similarities

Belongs to the TrhO family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    350
  • Mass (Da)
    39,735
  • Last updated
    2009-03-24 v1
  • Checksum
    61AB5F317B0C24DB
MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDALYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNKSRGRLNTTLGIPDPTE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU928164
EMBL· GenBank· DDBJ
CAR18236.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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