B7N4P2 · MAO1_ECOLU

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Divalent metal cations. Prefers magnesium or manganese.

Features

Showing features for active site, binding site, site.

TypeIDPosition(s)Description
Active site104Proton donor
Binding site157NAD+ (UniProtKB | ChEBI)
Active site175Proton acceptor
Binding site246a divalent metal cation (UniProtKB | ChEBI)
Binding site247a divalent metal cation (UniProtKB | ChEBI)
Binding site270a divalent metal cation (UniProtKB | ChEBI)
Binding site270NAD+ (UniProtKB | ChEBI)
Site270Important for activity
Binding site418NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmalate dehydrogenase (decarboxylating) (NAD+) activity
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular Functionoxaloacetate decarboxylase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD-dependent malic enzyme
  • EC number
  • Short names
    NAD-ME

Gene names

    • Name
      maeA
    • Ordered locus names
      ECUMN_1734

Organism names

Accessions

  • Primary accession
    B7N4P2

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001859961-565NAD-dependent malic enzyme

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the malic enzymes family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    565
  • Mass (Da)
    63,163
  • Last updated
    2009-03-24 v1
  • Checksum
    FFD2C913F7028F3A
MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU928163
EMBL· GenBank· DDBJ
CAR12936.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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