B5XTS2 · NFUA_KLEP3

Function

function

Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.

Features

Showing features for binding site.

119120406080100120140160180
TypeIDPosition(s)Description
Binding site149[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site152[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Biological Processiron-sulfur cluster assembly
Biological Processprotein maturation by iron-sulfur cluster transfer

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fe/S biogenesis protein NfuA

Gene names

    • Name
      nfuA
    • Ordered locus names
      KPK_0331

Organism names

  • Taxonomic identifier
  • Strain
    • 342
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella

Accessions

  • Primary accession
    B5XTS2

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001867551-191Fe/S biogenesis protein NfuA

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the NfuA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    191
  • Mass (Da)
    21,005
  • Last updated
    2008-11-25 v1
  • Checksum
    A755F3C75795A091
MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEDTDTALKFEQLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVSDDAPLMERVEYLLQSQINPQLAGHGGRVSLMEITDDGLAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000964
EMBL· GenBank· DDBJ
ACI07757.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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