B5DD91 · B5DD91_PSEPQ

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

136450100150200250300350
TypeIDPosition(s)Description
Binding site72Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site86Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site171Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site185Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site190a ubiquinone (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processrespiratory electron transport chain

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    B5DD91

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-45Helical
Transmembrane66-87Helical
Transmembrane102-122Helical
Transmembrane134-155Helical
Transmembrane167-189Helical
Transmembrane218-239Helical
Transmembrane277-297Helical
Transmembrane309-329Helical
Transmembrane335-354Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-198Cytochrome b/b6 N-terminal region profile
Domain199-364Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    364
  • Mass (Da)
    40,815
  • Last updated
    2008-10-14 v1
  • Checksum
    40E030FAFB0AF08E
KIVNDALIDLPAPSNISAWWNFGSLLLLCLMMQIMTGLFLAMHYTSDISTAFSSVAHICRDVNYGWIIRNLHANGASFFFICIYLHIGRGLYYGSYLYKETWNIGVILLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYMGDMLVQWIWGGFSVDNATLTRFFAFHFLLPFAVVAATLLHALFLHETGSNNPLGLNSDADKISFHPYFSYKDILGFILLLTALASLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMVVPLLHTSKQQGLTFRPIAQFMFWVLVADVMILTWIGGMPVEHPFIIIGQIASVLYFSLFLILNPLTGWLENK

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue364

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY912419
EMBL· GenBank· DDBJ
AAX93654.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912420
EMBL· GenBank· DDBJ
AAX93655.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912421
EMBL· GenBank· DDBJ
AAX93656.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912422
EMBL· GenBank· DDBJ
AAX93657.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912423
EMBL· GenBank· DDBJ
AAX93658.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912424
EMBL· GenBank· DDBJ
AAX93659.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912425
EMBL· GenBank· DDBJ
AAX93660.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912426
EMBL· GenBank· DDBJ
AAX93661.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912427
EMBL· GenBank· DDBJ
AAX93662.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912428
EMBL· GenBank· DDBJ
AAX93663.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912429
EMBL· GenBank· DDBJ
AAX93664.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912431
EMBL· GenBank· DDBJ
AAX93666.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912432
EMBL· GenBank· DDBJ
AAX93667.1
EMBL· GenBank· DDBJ
Genomic DNA
AY912437
EMBL· GenBank· DDBJ
AAX93672.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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