B4TGV9 · IDI_SALHS

Function

function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit. The magnesium ion binds only when substrate is bound.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mn2+ ion per subunit.

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site25Mn2+ (UniProtKB | ChEBI)
Binding site32Mn2+ (UniProtKB | ChEBI)
Active site67
Binding site69Mn2+ (UniProtKB | ChEBI)
Binding site87Mg2+ (UniProtKB | ChEBI)
Binding site114Mn2+ (UniProtKB | ChEBI)
Active site116
Binding site116Mn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionisopentenyl-diphosphate delta-isomerase activity
Molecular Functionmetal ion binding
Biological Processdimethylallyl diphosphate biosynthetic process
Biological Processisoprenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isopentenyl-diphosphate Delta-isomerase
  • EC number
  • Short names
    IPP isomerase
  • Alternative names
    • IPP:DMAPP isomerase
    • Isopentenyl pyrophosphate isomerase

Gene names

    • Name
      idi
    • Ordered locus names
      SeHA_C3270

Organism names

Accessions

  • Primary accession
    B4TGV9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000994441-181Isopentenyl-diphosphate Delta-isomerase

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain30-164Nudix hydrolase

Sequence similarities

Belongs to the IPP isomerase type 1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    181
  • Mass (Da)
    20,781
  • Last updated
    2008-09-23 v1
  • Checksum
    1B0EBEA813936526
MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDGQLLVTRRSLSKKAWPGVWTNSVCGHPQQGETTEEAIIRRCRFELGVEITDLTPVYPHFSYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWKSLLATPWAFSPWMVMQASDEQARERLLNYCQR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001120
EMBL· GenBank· DDBJ
ACF67957.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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