B4RFG1 · MURB_PHEZH
- ProteinUDP-N-acetylenolpyruvoylglucosamine reductase
- GenemurB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids300 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation.
Catalytic activity
- NADP+ + UDP-N-acetyl-alpha-D-muramate = H+ + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine
Cofactor
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 172 | |||||
Sequence: R | ||||||
Active site | 223 | Proton donor | ||||
Sequence: S | ||||||
Active site | 293 | |||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | FAD binding | |
Molecular Function | UDP-N-acetylmuramate dehydrogenase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylenolpyruvoylglucosamine reductase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Caulobacterales > Caulobacteraceae > Phenylobacterium
Accessions
- Primary accessionB4RFG1
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000191438 | 1-300 | UDP-N-acetylenolpyruvoylglucosamine reductase | |||
Sequence: MTWKDRLPAVRGKLLRDEPLAPFTWFRVGGPADVIFLPEDEDDLAAFLKALPAEVPVTVLGVGSNTLVRDGGVDGVVIRLGKAFAKVEPRGEGRLYAGAAALDAVVAREAGKAGIAGLEFYRGVPGTIGGALVMNAGCYGAETKDVLVEAYALTRAGERLTLSNADLGYSYRKSARAAAEPLIFLGALFEGRPDDPAAIEARMAEITERREKTQPIREKTGGSTFKNPPGHSSWKLVDEAGWRGKLFGGAMFSPLHSNFLINTGEATAADLEGLGEAVRADVKAKFGVDLDWEIKRIGRP |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 27-216 | FAD-binding PCMH-type | ||||
Sequence: RVGGPADVIFLPEDEDDLAAFLKALPAEVPVTVLGVGSNTLVRDGGVDGVVIRLGKAFAKVEPRGEGRLYAGAAALDAVVAREAGKAGIAGLEFYRGVPGTIGGALVMNAGCYGAETKDVLVEAYALTRAGERLTLSNADLGYSYRKSARAAAEPLIFLGALFEGRPDDPAAIEARMAEITERREKTQPI |
Sequence similarities
Belongs to the MurB family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length300
- Mass (Da)32,008
- Last updated2008-09-23 v1
- Checksum61251C19CB0731BB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000747 EMBL· GenBank· DDBJ | ACG78731.1 EMBL· GenBank· DDBJ | Genomic DNA |