B3PXU3 · SYS_RHIE6

Function

function

Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).

Catalytic activity

Pathway

Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site231-233L-serine (UniProtKB | ChEBI)
Binding site262-264ATP (UniProtKB | ChEBI)
Binding site285L-serine (UniProtKB | ChEBI)
Binding site349-352ATP (UniProtKB | ChEBI)
Binding site385L-serine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionserine-tRNA ligase activity
Biological Processselenocysteine biosynthetic process
Biological Processseryl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine--tRNA ligase
  • EC number
  • Alternative names
    • Seryl-tRNA synthetase
      (SerRS
      )
    • Seryl-tRNA(Ser/Sec) synthetase

Gene names

    • Name
      serS
    • Ordered locus names
      RHECIAT_CH0001912

Organism names

  • Taxonomic identifier
  • Strain
    • CIAT 652
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Rhizobium

Accessions

  • Primary accession
    B3PXU3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000981121-427Serine--tRNA ligase

Interaction

Subunit

Homodimer. The tRNA molecule binds across the dimer.

Structure

Family & Domains

Domain

Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    427
  • Mass (Da)
    47,781
  • Last updated
    2008-09-02 v1
  • Checksum
    053AC768B75CDF5C
MLDIKWIRENPEALDAALAKRGAEPQAQSLVALDEKRRSAVQKAQDMLSRRNLASKEIGAAMAQKNGELAEKLKAEVAELKTLLPAIEEEDRQLTAELNDALSRIPNIPFDDVPVGKDEHDNVVTRTVGEKPRWNHTPKEHFEIGEALGYMDFERAAKLSGSRFTVLTGPLARLERALGQFMIDLHTREHGYTEVSSPLMVRAEALFGTGNLPKFEEDLFKTTDDRYLIPTAEVTLTNLVREEILEQEKLPLRFTALTPSFRSEAGSAGRDTRGMLRQHQFWKCELVSITDADSAIAEHERMTACAEEVLKRLGLHFRTMTLCTGDMGFGSRKTYDLEVWLPGQNAFREISSCSVCGDFQARRMNARYRGKDDKTNRFVHTLNGSGTAVGRCLIAVLENYLNEDGSVTIPDVLLPYMGGLTKIERAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001074
EMBL· GenBank· DDBJ
ACE90879.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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