B0BZH9 · PUR9_ACAM1

Function

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.
Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionIMP cyclohydrolase activity
Molecular Functionphosphoribosylaminoimidazolecarboxamide formyltransferase activity
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional purine biosynthesis protein PurH

Including 2 domains:

  • Recommended name
    Phosphoribosylaminoimidazolecarboxamide formyltransferase
  • EC number
  • Alternative names
    • AICAR transformylase
  • Recommended name
    IMP cyclohydrolase
  • EC number
  • Alternative names
    • ATIC
    • IMP synthase
    • Inosinicase

Gene names

    • Name
      purH
    • Ordered locus names
      AM1_5779

Organism names

Accessions

  • Primary accession
    B0BZH9

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000764721-524Bifunctional purine biosynthesis protein PurH

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-154MGS-like

Domain

The IMP cyclohydrolase activity resides in the N-terminal region.

Sequence similarities

Belongs to the PurH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    524
  • Mass (Da)
    55,848
  • Last updated
    2008-02-26 v1
  • Checksum
    E979D0DFD30BA415
MTRLALLSTSDKTGLVELAQQLVNEYGFTLVSSGGTAVTIEKAGLPVTKVSDYTGSPEILGGRVKTLHPRIHGGILARRSLESDVQDLTENNIQGIDLVVVNLYPFEETIAKQKAQGITDPDQALADAVEQIDIGGPTMIRAAAKNHAHVTVLCDPQQYASYLQELKHGEGETSLPFRQACALKVFERMASYDRAIATHLRQSLATTDSQTQLSILGTAKQTLRYGENPHQNAVWYQESDTASGWAAAQQLQGKELSYNNLVDLEAARRVIAEFAQAETQPTVAILKHNNPCGVAQGETLLQAYEKALAADSVSAFGGIVAMNRAIDTDTAQVLTKTFLECIVAPECQPEAAAVLQAKSNLRVLVLPDLVSGPAVTVKAIAGGWLAQAADETLTPPADWQIVTQAKPTEAQLAELLFAWKVVKHVKSNAIVVTKDHTTLGVGAGQMNRVGSVNIALQQAGEKAQGGTLASDGFFPFDDSVRTAAAAGITAIIQPGGSIRDKDSIQAADELGIVMAFTGTRHFLH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000828
EMBL· GenBank· DDBJ
ABW30724.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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