A9VY77 · PIMT_METEP

Function

function

Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

Catalytic activity

Features

Showing features for active site.

122820406080100120140160180200220
TypeIDPosition(s)Description
Active site74

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionprotein-L-isoaspartate (D-aspartate) O-methyltransferase activity
Biological Processmethylation
Biological Processprotein modification process
Biological Processprotein repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-L-isoaspartate O-methyltransferase
  • EC number
  • Alternative names
    • L-isoaspartyl protein carboxyl methyltransferase
    • Protein L-isoaspartyl methyltransferase
    • Protein-beta-aspartate methyltransferase
      (PIMT
      )

Gene names

    • Name
      pcm
    • Ordered locus names
      Mext_4262

Organism names

Accessions

  • Primary accession
    A9VY77

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003518801-228Protein-L-isoaspartate O-methyltransferase

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    228
  • Mass (Da)
    23,848
  • Last updated
    2008-02-05 v1
  • Checksum
    8C74B928673B697E
MPGRTAPTRSEPVPDRAEARTRMVETQLVARGIRDAAVLDAMRAVPREAFVPDALAGEAYGDGPLPIGVGQTISQPYIVALMIEALALRPGDRVLEVGAGCGYAAAVLARMGVQVFAIERHAALGEAARARLAALGLTVSLRIGDGHAGWPEAAPFDAILVSAAGSTIPEALKAQLKPRGRLVIPVGPPGGQTLLRLTRRGRDRFESRDFGPVSFVPLLRGVGTADPV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000908
EMBL· GenBank· DDBJ
ABY32631.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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