A9M3A0 · UBIE_NEIM0
- ProteinUbiquinone/menaquinone biosynthesis C-methyltransferase UbiE
- GeneubiE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids245 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
Catalytic activity
- a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + S-adenosyl-L-homocysteine + H+
a 2-demethylmenaquinol RHEA-COMP:9563 + CHEBI:59789 = a menaquinol RHEA-COMP:9539 + CHEBI:57856 + CHEBI:15378
Pathway
Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.
Cofactor biosynthesis; ubiquinone biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity | |
Molecular Function | demethylmenaquinone methyltransferase activity | |
Biological Process | aerobic respiration | |
Biological Process | menaquinone biosynthetic process | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUbiquinone/menaquinone biosynthesis C-methyltransferase UbiE
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria
Accessions
- Primary accessionA9M3A0
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000088286 | 1-245 | Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE | |||
Sequence: MGGQKTHFGFSTVNEDEKAGKVAEVFHSVAKNYDIMNDVMSAGLHRVWKHFTINTAHLKKGDKVLDIAGGTGDLSRGWAKRVGKEGEVWLTDINSSMLTVGRDCLLNEGMILPVSLADAEKLPFPDNYFNLVSVAFGLRNMTHKDTALKEMCRVLKPGGTLLVLEFSKIYKPLEGAYDFYSFKLLPVMGKLIAKDAESYQYLAESIRMHPDQETLKQMMLDAGFDSVDYHNMSAGIVALHKGVKF |
Structure
Sequence
- Sequence statusComplete
- Length245
- Mass (Da)27,254
- Last updated2008-02-05 v1
- Checksum4F447E85396D3371
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000381 EMBL· GenBank· DDBJ | ABX72900.1 EMBL· GenBank· DDBJ | Genomic DNA |