A8JPF9 · STUA_COLGL
- ProteinCell pattern formation-associated protein STUA
- GeneSTUA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids617 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Transcription factor that regulates asexual reproduction (By similarity).
Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).
Required for the formation of aerial hyphae, efficient conidiation, and the formation of perithecia (PubMed:17849713).
Essential for the generation of normal turgor pressure within the appressorium (PubMed:17849713).
Required for infection of intact apple fruit and penetration of onion epidermal cells (PubMed:17849713).
Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).
Required for the formation of aerial hyphae, efficient conidiation, and the formation of perithecia (PubMed:17849713).
Essential for the generation of normal turgor pressure within the appressorium (PubMed:17849713).
Required for infection of intact apple fruit and penetration of onion epidermal cells (PubMed:17849713).
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 140-161 | H-T-H motif | ||||
Sequence: GTKLLNVAGMTRGRRDGILKSE |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | sequence-specific DNA binding | |
Biological Process | conidium formation | |
Biological Process | positive regulation of transcription by RNA polymerase II | |
Biological Process | sporulation resulting in formation of a cellular spore |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCell pattern formation-associated protein STUA
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Glomerellales > Glomerellaceae > Colletotrichum > Colletotrichum gloeosporioides species complex
Accessions
- Primary accessionA8JPF9
Subcellular Location
Phenotypes & Variants
Disruption phenotype
Impairs conidiation and ability of their appressoria to form a penetration peg, leading to unability to infect unwounded Granny Smith apples or onion (PubMed:17849713).
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000435972 | 1-617 | Cell pattern formation-associated protein STUA | |||
Sequence: MNQPAADMYYSQHMSAGQAPPPQTVTSGAMSYHSQHPPLQPTHMPQYAPQPQYSQYGYANGLTSPQSAQPASQMGQNVLPLPGVATQGFQGFDTTGQVAPPGMKPRVTATLWEDEGSLCFQVEARGICVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPFERALDFANKEKITELLYPLFVHNIGALLYHPTNQTRTNQVMAAAERRKQEQNQMRGAPQTGAPGLPSIQQHHHHMSLPGPQQSLPSHAQMGRPSLDRAHTFPTPPTSASSVMGGNMNASDSGFQWAQGQGMGSAQGANPMSIDTGLSNARSMPATPASTPPGTTIQNMQSYQSGAQQYDNSRPMYNPSAQQSPYQATNPASQDRPVYGQPDPYAKNDMGPPTTRPATSGAPQDQKPANGIIHADQSGGQPAGDEEAEHDHDAEYTHDSGAYDASRASYNYSAPAVGNLPAEHQHLSPEMTGSPSHPPASGRATPRTAAAPQPYYSQQAGYNTPPRVPQQPSSNLYNVMSNDRGTAAGAGTGDVYQPQADMGSMSNGYASQMNGAGGIKRGRDEDDDLQRPSSGGGMDLKRRKTLLDSQVPAMAYAPPVMAQQPRRR |
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-79 | Disordered | ||||
Sequence: MNQPAADMYYSQHMSAGQAPPPQTVTSGAMSYHSQHPPLQPTHMPQYAPQPQYSQYGYANGLTSPQSAQPASQMGQNVL | ||||||
Compositional bias | 16-79 | Polar residues | ||||
Sequence: AGQAPPPQTVTSGAMSYHSQHPPLQPTHMPQYAPQPQYSQYGYANGLTSPQSAQPASQMGQNVL | ||||||
Domain | 106-212 | HTH APSES-type | ||||
Sequence: RVTATLWEDEGSLCFQVEARGICVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPFERALDFANKEKITELLYPLFVHNIGALLYHP | ||||||
Region | 223-274 | Disordered | ||||
Sequence: AAAERRKQEQNQMRGAPQTGAPGLPSIQQHHHHMSLPGPQQSLPSHAQMGRP | ||||||
Compositional bias | 255-270 | Polar residues | ||||
Sequence: HMSLPGPQQSLPSHAQ | ||||||
Compositional bias | 300-385 | Polar residues | ||||
Sequence: SDSGFQWAQGQGMGSAQGANPMSIDTGLSNARSMPATPASTPPGTTIQNMQSYQSGAQQYDNSRPMYNPSAQQSPYQATNPASQDR | ||||||
Region | 300-451 | Disordered | ||||
Sequence: SDSGFQWAQGQGMGSAQGANPMSIDTGLSNARSMPATPASTPPGTTIQNMQSYQSGAQQYDNSRPMYNPSAQQSPYQATNPASQDRPVYGQPDPYAKNDMGPPTTRPATSGAPQDQKPANGIIHADQSGGQPAGDEEAEHDHDAEYTHDSGA | ||||||
Compositional bias | 432-449 | Basic and acidic residues | ||||
Sequence: AGDEEAEHDHDAEYTHDS | ||||||
Region | 463-617 | Disordered | ||||
Sequence: APAVGNLPAEHQHLSPEMTGSPSHPPASGRATPRTAAAPQPYYSQQAGYNTPPRVPQQPSSNLYNVMSNDRGTAAGAGTGDVYQPQADMGSMSNGYASQMNGAGGIKRGRDEDDDLQRPSSGGGMDLKRRKTLLDSQVPAMAYAPPVMAQQPRRR | ||||||
Compositional bias | 500-531 | Polar residues | ||||
Sequence: APQPYYSQQAGYNTPPRVPQQPSSNLYNVMSN | ||||||
Compositional bias | 548-562 | Polar residues | ||||
Sequence: QADMGSMSNGYASQM | ||||||
Compositional bias | 568-595 | Basic and acidic residues | ||||
Sequence: IKRGRDEDDDLQRPSSGGGMDLKRRKTL | ||||||
Region | 569-593 | Nuclear localization domain | ||||
Sequence: KRGRDEDDDLQRPSSGGGMDLKRRK |
Sequence similarities
Belongs to the EFG1/PHD1/stuA family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length617
- Mass (Da)66,198
- Last updated2016-04-13 v2
- Checksum7761C77F072BFFFE
Sequence caution
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 16-79 | Polar residues | ||||
Sequence: AGQAPPPQTVTSGAMSYHSQHPPLQPTHMPQYAPQPQYSQYGYANGLTSPQSAQPASQMGQNVL | ||||||
Compositional bias | 255-270 | Polar residues | ||||
Sequence: HMSLPGPQQSLPSHAQ | ||||||
Compositional bias | 300-385 | Polar residues | ||||
Sequence: SDSGFQWAQGQGMGSAQGANPMSIDTGLSNARSMPATPASTPPGTTIQNMQSYQSGAQQYDNSRPMYNPSAQQSPYQATNPASQDR | ||||||
Compositional bias | 432-449 | Basic and acidic residues | ||||
Sequence: AGDEEAEHDHDAEYTHDS | ||||||
Compositional bias | 500-531 | Polar residues | ||||
Sequence: APQPYYSQQAGYNTPPRVPQQPSSNLYNVMSN | ||||||
Compositional bias | 548-562 | Polar residues | ||||
Sequence: QADMGSMSNGYASQM | ||||||
Compositional bias | 568-595 | Basic and acidic residues | ||||
Sequence: IKRGRDEDDDLQRPSSGGGMDLKRRKTL |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EF408244 EMBL· GenBank· DDBJ | ABQ43358.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation | |
EF408244 EMBL· GenBank· DDBJ | ABQ43363.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation | |
EF634312 EMBL· GenBank· DDBJ | ABV00676.1 EMBL· GenBank· DDBJ | mRNA | Different initiation |