A4S3R2 · GUF1_OSTLU
- ProteinTranslation factor GUF1 homolog, mitochondrial
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids651 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Miscellaneous
This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Catalytic activity
- GTP + H2O = GDP + H+ + phosphate
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | mitochondrial matrix | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | mitochondrial ribosome binding | |
Biological Process | positive regulation of translation | |
Biological Process | translation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTranslation factor GUF1 homolog, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Chlorophyta > Mamiellophyceae > Mamiellales > Bathycoccaceae > Ostreococcus
Accessions
- Primary accessionA4S3R2
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000402846 | 1-651 | Translation factor GUF1 homolog, mitochondrial | |||
Sequence: MALRRVLVDRIVRSCAARAFASTSASYASARDALKEERPPTADELAAIPRERTRNFSIIAHVDHGKSTLADRLLELTGAIKRDGSNKQVLDTLPVERRRGITVKAQAVSILHREPSDGQAYLLNLIDTPGHADFSFEVSRSLSACDGAVMLVDATQGVEAQTIATFYLALDRNLAIVPAANKVDMTSADVERVAKQMERAFGVEREDVLEVSGKTGHNAEKVLSAVVKHVPHPSGDPNGPLRVLLLDCHYDDYRGAVNIVQVADGVIRKGDKVSSCASGQHFEVLELGMMTPERTKTDAMYAGQVGYMITNVRDVRSSKVGDTLHMKNEPVEPLAGIRPAKPMVFQGLYPVNSDDFEKLKAAVSKLTLNDASVTAQTENSTALGAGFRCGFLGLLHADVFHQRLQEEFGAEIIATAPTVPYRIKHANDEAYIDCTSPLAIPSGGFPSKGTEIEEPLVEATIICQPHVVGKVVELCMDRRGEQLEQNFLDDSRVILRYRLPLGEVAADFADELKSRSSGYATFDYDDAGMAKSDIVRMDVLVNGSVVDALATLVHRSKAQRHGRDLVARLKEALPRQLYEVALQAALGSKVIARETISAMRKNVTAKCYGGDISRKKKLLEKQKEGKRRMRRIGNVDIPNETFAGILSNKRN |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 51-234 | tr-type G | ||||
Sequence: ERTRNFSIIAHVDHGKSTLADRLLELTGAIKRDGSNKQVLDTLPVERRRGITVKAQAVSILHREPSDGQAYLLNLIDTPGHADFSFEVSRSLSACDGAVMLVDATQGVEAQTIATFYLALDRNLAIVPAANKVDMTSADVERVAKQMERAFGVEREDVLEVSGKTGHNAEKVLSAVVKHVPHPS |
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length651
- Mass (Da)71,192
- Last updated2007-05-15 v1
- ChecksumEF96BAE705144E55
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000590 EMBL· GenBank· DDBJ | ABO98431.1 EMBL· GenBank· DDBJ | Genomic DNA |