A3QBR5 · NHAA_SHELP

Function

function

Na+/H+ antiporter that extrudes sodium in exchange for external protons.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionsodium:proton antiporter activity
Biological Processregulation of pH

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Na(+)/H(+) antiporter NhaA
  • Alternative names
    • Sodium/proton antiporter NhaA

Gene names

    • Name
      nhaA
    • Ordered locus names
      Shew_1042

Organism names

Accessions

  • Primary accession
    A3QBR5

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane14-34Helical
Transmembrane59-79Helical
Transmembrane95-115Helical
Transmembrane124-144Helical
Transmembrane154-174Helical
Transmembrane177-197Helical
Transmembrane213-233Helical
Transmembrane261-281Helical
Transmembrane292-312Helical
Transmembrane331-351Helical
Transmembrane363-383Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003344261-391Na+/H+ antiporter NhaA

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    391
  • Mass (Da)
    41,245
  • Last updated
    2007-04-17 v1
  • Checksum
    A42F89B8AD738241
MEKAIRNFLSQESAGGILLMAAVILAMIMANSPLSGLYQGFLHTEMQVRVGSLDIDKTLIHWINDGLMALFFMLIGLEVKRELLEGALSSREQASLPTFAAIGGMIFPAAIYLIFNYADPITQVGWAIPAATDIAFALGIMALLGSRVPVALKVFLLALAIIDDLGVVVIIAMFYSTDLSAISLVVAALAIVILVGLNRKGVTALAPYGVVGLILWIAVLKSGVHATLAGVIIAFCIPLRAKDGSSPSEHLEHSLHPWSTFVILPIFAFANAGVDLSGMSLGDLLSPVPVGIALGLLLGKPLGVLLFSFVAVKLKLAALPEGMGWRHIAPVAVMCGIGFTMSMFISSLAFIGDGEAYGDLARLGILTGSIMSAVIGYFWLSKVLPEKGEKS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000606
EMBL· GenBank· DDBJ
ABO22913.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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