A3PJQ3 · ISPD_CERS1

Function

function

Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.

Features

Showing features for site.

122520406080100120140160180200220
TypeIDPosition(s)Description
Site15Transition state stabilizer
Site22Transition state stabilizer
Site152Positions MEP for the nucleophilic attack
Site205Positions MEP for the nucleophilic attack

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
  • EC number
  • Alternative names
    • 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
    • MEP cytidylyltransferase
      (MCT
      )

Gene names

    • Name
      ispD
    • Ordered locus names
      Rsph17029_1459

Organism names

Accessions

  • Primary accession
    A3PJQ3

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000229431-2252-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Structure

Family & Domains

Sequence similarities

Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    225
  • Mass (Da)
    23,026
  • Last updated
    2007-04-03 v1
  • Checksum
    04558F8E98AA89FE
MTTAAIIVAAGRGTRAGGDLPKQWQPLAGRPVLAHTLAAFRAAAGVSRTLLVIHPDDRARAEALPGVAEGKVELVEGGASRDASVRNALEALAGAGIERVLIHDGARPLVAPGLIARTLAALETAPGAAPAVPVSDALWRGEGGRVVGTQDRTGLFRAQTPQAFRYEAILAAHRAHPGGAADDVEVARAAGLEVAIVEGCEDNLKVTYPGDFARAERLLALAAGL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000577
EMBL· GenBank· DDBJ
ABN76569.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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