A2BQT3 · HIS4_PROMS

  • Protein
    1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
  • Gene
    hisA
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Catalytic activity

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.

Features

Showing features for active site.

125520406080100120140160180200220240
TypeIDPosition(s)Description
Active site8Proton acceptor
Active site129Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
Biological ProcessL-histidine biosynthetic process
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
  • EC number
  • Alternative names
    • Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase

Gene names

    • Name
      hisA
    • Ordered locus names
      A9601_08601

Organism names

Accessions

  • Primary accession
    A2BQT3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002905071-2551-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the HisA/HisF family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    255
  • Mass (Da)
    28,172
  • Last updated
    2007-02-20 v1
  • Checksum
    F3ECF7C52AC59E53
MDLIPAIDLMNGKCVRLFKGDFNKRKDFAKEPHEQAEFWEREGAKYIHIVDLDAAKTGSPTNDKSIKKIAKTVNIPIQIGGGIRSQERIEQLFSYGVEKVIMGTSAIENKELVKDLSNKFPGRIIVGIDAKDGKVSTRGWLEQSNIFATDLVKEFSSFKIASFIVTDINTDGTLEGTNEEFIKSILEITDIPVIASGGVGSISDLLSLVKFENSGLFGVIVGKALYENKFTINEANNVLSAERLNDIDLNTNYYA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000551
EMBL· GenBank· DDBJ
ABM70144.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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