A1SLK7 · IF2_NOCSJ

Function

function

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

Features

Showing features for binding site.

1938100200300400500600700800900
TypeIDPosition(s)Description
Binding site440-447GTP (UniProtKB | ChEBI)
Binding site490-494GTP (UniProtKB | ChEBI)
Binding site544-547GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functiontranslation initiation factor activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Translation initiation factor IF-2

Gene names

    • Name
      infB
    • Ordered locus names
      Noca_3190

Organism names

Accessions

  • Primary accession
    A1SLK7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000082901-938Translation initiation factor IF-2

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region55-322Disordered
Compositional bias116-140Pro residues
Compositional bias152-168Pro residues
Compositional bias194-208Pro residues
Domain431-603tr-type G
Region440-447G1
Region465-469G2
Region490-493G3
Region544-547G4
Region580-582G5

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    938
  • Mass (Da)
    98,291
  • Last updated
    2007-02-06 v1
  • Checksum
    7BBD39D7B5DF10A8
MAKTRVHELAKEFGVESKFVLEKFKEMGEFVKSASSTVELPAEMRFRKEYGEKLKAEASAAPAAPAEKPAAKKAPAKKAAATAEPEALAAEPAAEPAAAEAPAAAEAEAPAAKAAAPKPGPKPAPVAEQPAPPAEPEAPEAPEAPAASAAPAAPKAPAPRPVGRPGAPRPGNNPFASSQGMGRRPAPGAPAAPGAGDNRPPRPPAAREGGVPGRPGMPRPNPAMMPKSPSAFGAGPGGRGPARPGAPGRGGAPGRGGAPGRGGVGTGAPGRGGAPGGGFGPSGGGRPGGGRPGQRGQTQGAFGRPGGPSRRGRKSKRARRQEFEAMEAPTIGGIRVRKGNGETVRLPRGASLTDFAERINVEPAQLVQMLFSLGEMVTATESVNDETLELLGEELNYVVEVVSPEDEDRELLESFDIEFADDEDDEGHFEARPPVVTVMGHVDHGKTKLLDALRHANVASGEAGGITQHIGAYQVHTDVDGEDRKITFIDTPGHEAFTAMRARGSQSSDIAVLVVAADDGVMPQTVEALNHAKAAGVPIVVAVNKIDKPEADPTKVRGQLTEYGLVPEEYGGDTMFVDVSAKSELNLDKLLEAVVLTADASLDLRANPNRDAQGLVIEAHLDRGRGPVATILVQRGTLHVGDSIVAGPAHGRVRAMLDEYGNELTEATPSRPAMVLGLSTVPGAGQNFIVVEDDRMARQIAEKREARERAAMQAKRRVRRTLEDFMASMEKGESQELNLILKGDVSGSVEALEDALAKIDVGDDVSLRVIDRGVGAITETNVDLAAASDAIIIGFNVRPQGKATELADREGVEIRYYTVIYQAIEEIEAALKGMLKPEFEESTLGQAEIRAIFRSSKVGNIAGCMVISGVIRRNAKVRVIRDGAVVADNLDLASLKREKDDASEVREGFECGLVLRNFQDIKEGDIVEAFEMREIPRA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias116-140Pro residues
Compositional bias152-168Pro residues
Compositional bias194-208Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000509
EMBL· GenBank· DDBJ
ABL82692.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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