A1SJN0 · COBS_NOCSJ

Function

function

Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenosylcobinamide-GDP ribazoletransferase activity
Molecular Functioncobalamin 5'-phosphate synthase activity
Biological Processcobalamin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylcobinamide-GDP ribazoletransferase
  • EC number
  • Alternative names
    • Cobalamin synthase
    • Cobalamin-5'-phosphate synthase

Gene names

    • Name
      cobS
    • Ordered locus names
      Noca_2511

Organism names

Accessions

  • Primary accession
    A1SJN0

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane31-51Helical
Transmembrane55-75Helical
Transmembrane111-131Helical
Transmembrane134-154Helical
Transmembrane176-196Helical
Transmembrane208-228Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001325891-229Adenosylcobinamide-GDP ribazoletransferase

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the CobS family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    229
  • Mass (Da)
    23,052
  • Last updated
    2007-02-06 v1
  • Checksum
    71A27E8B0C7C452A
MRDAWRFAVGTLTALPVRPPTRVDRDTARRAMLLAPLAALPLGLLVAAVLAAGRAVELPPLAVGLLAVGALAASSRALHWDGLSDTVDGLAASYDPARSLAVMRSGTSGPAGVLATVVVAGVQAAALATLLDQPLLAGALVCLSRCALWIVCCTRVPAARADGLGADVARTVPLPVAVLGGLLLSAVGGLVVLVLVRRTVRRFGGVTGDVMGAAVELALAATLLAWAAR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000509
EMBL· GenBank· DDBJ
ABL82015.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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