A1SJN0 · COBS_NOCSJ
- ProteinAdenosylcobinamide-GDP ribazoletransferase
- GenecobS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids229 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Catalytic activity
- adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H+
Cofactor
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | adenosylcobinamide-GDP ribazoletransferase activity | |
Molecular Function | cobalamin 5'-phosphate synthase activity | |
Biological Process | cobalamin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenosylcobinamide-GDP ribazoletransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Propionibacteriales > Nocardioidaceae > Nocardioides
Accessions
- Primary accessionA1SJN0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 31-51 | Helical | ||||
Sequence: AMLLAPLAALPLGLLVAAVLA | ||||||
Transmembrane | 55-75 | Helical | ||||
Sequence: AVELPPLAVGLLAVGALAASS | ||||||
Transmembrane | 111-131 | Helical | ||||
Sequence: AGVLATVVVAGVQAAALATLL | ||||||
Transmembrane | 134-154 | Helical | ||||
Sequence: PLLAGALVCLSRCALWIVCCT | ||||||
Transmembrane | 176-196 | Helical | ||||
Sequence: VAVLGGLLLSAVGGLVVLVLV | ||||||
Transmembrane | 208-228 | Helical | ||||
Sequence: GDVMGAAVELALAATLLAWAA |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000132589 | 1-229 | Adenosylcobinamide-GDP ribazoletransferase | |||
Sequence: MRDAWRFAVGTLTALPVRPPTRVDRDTARRAMLLAPLAALPLGLLVAAVLAAGRAVELPPLAVGLLAVGALAASSRALHWDGLSDTVDGLAASYDPARSLAVMRSGTSGPAGVLATVVVAGVQAAALATLLDQPLLAGALVCLSRCALWIVCCTRVPAARADGLGADVARTVPLPVAVLGGLLLSAVGGLVVLVLVRRTVRRFGGVTGDVMGAAVELALAATLLAWAAR |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length229
- Mass (Da)23,052
- Last updated2007-02-06 v1
- Checksum71A27E8B0C7C452A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000509 EMBL· GenBank· DDBJ | ABL82015.1 EMBL· GenBank· DDBJ | Genomic DNA |