A1ALC4 · FMT_PELPD
- ProteinMethionyl-tRNA formyltransferase
- Genefmt
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids319 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
Catalytic activity
- L-methionyl-tRNA(fMet) + (6R)-10-formyltetrahydrofolate = N-formyl-L-methionyl-tRNA(fMet) + (6S)-5,6,7,8-tetrahydrofolate + H+
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | methionyl-tRNA formyltransferase activity |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionyl-tRNA formyltransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfuromonadia > Desulfuromonadales > Desulfuromonadaceae > Pelobacter
Accessions
- Primary accessionA1ALC4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000020120 | 1-319 | Methionyl-tRNA formyltransferase | |||
Sequence: MSSRSIVFMGTPEFACPTLQALIDRGERLLAVVTQPDRPKGRGHKLMPPPVKELALAHDIPVLQPHRVRASAFVESIRQLAPELIVVVAFGQILPKALLDIPPLGCVNVHASLLPRYRGAAPLNWCIINGETETGVTTMLMDTGLDTGPMLLKRSTPIDENEDIVSLHDRMASLGAELLAETLDGLREGRIEPQPQNDSLSCYAPLLKKEHGLIDWQRPARQIHNQVRGLAAWPGAQTLLNGHALKLFRTRVADGAGAPGTVLCSTGGQLEVACLDGSLLIQELQLAGKKRLDSASFLAGCPIAEGTLLGGAATERPIP |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length319
- Mass (Da)34,234
- Last updated2007-01-23 v1
- Checksum26D0863B8A86E267
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000482 EMBL· GenBank· DDBJ | ABK98144.1 EMBL· GenBank· DDBJ | Genomic DNA |