A0R109 · OCTT_MYCS2

Function

function

Sugar octanoyltransferase likely involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharide (MGLP). Catalyzes the transfer of an octanoyl group from octanoyl-CoA to the C6 OH of the second glucose in diglucosylglycerate (DGG). DGG is the preferred acceptor, but to a lesser extent, GG (glucosylglycerate) can also be used as substrate. DGG and GG are the two earliest intermediates in MGLP biosynthesis.

Catalytic activity

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
20 mMdiglucosylglycerate37
19 mMglucosylglycerate37
0.03 mMoctanoyl-CoA37when DGG is used as cosubstrate
0.02 μMoctanoyl-CoA37when GG is used as cosubstrate
Vmax pH TEMPERATURE[C] NOTES EVIDENCE
1939 nmol/min/mg37with diglucosylglycerate and octanoyl-CoA as substrates
20 nmol/min/mg37with glucosylglycerate and octanoyl-CoA as substrates

GO annotations

AspectTerm
Molecular FunctionO-octanoyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Diglucosylglycerate octanoyltransferase
  • EC number
  • Short names
    DGG octanoyltransferase

Gene names

    • Name
      octT
    • Ordered locus names
      MSMEG_4578
      , MSMEI_4466

Organism names

Accessions

  • Primary accession
    A0R109

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004369121-252Diglucosylglycerate octanoyltransferase

Proteomic databases

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the OctT acyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    252
  • Mass (Da)
    27,762
  • Last updated
    2007-01-09 v1
  • Checksum
    87247413D1175822
MSSETSSESTGHRPVLLVFADSLSYFGPTGGLPADDPRIWPNIVGEQLGWDVELIGRIGWTCRDVWWAATQDPRSWAALPRAGAVVFATSGMDSLPSPLPTALREMIRYVRPPWLRRWVRDGYGWVQPRLSPIARSALPPHVTVEYLEMTRNAIDFNRPGIPVVASLPSVHIAETYGRAHHGREPTVRAITAWAEEHHVPLVDLKAAVADEVFGGRGNPDGIHWSFEAHRAVAELMLKGLAEAGVTQRDSAT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000480
EMBL· GenBank· DDBJ
ABK73636.1
EMBL· GenBank· DDBJ
Genomic DNA
CP001663
EMBL· GenBank· DDBJ
AFP40920.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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