A0A851BHA0 · A0A851BHA0_PICGY
- ProteinTyrosine-protein kinase
- GeneLck_0
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids321 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- ATP + L-tyrosyl-[protein] = ADP + H+ + O-phospho-L-tyrosyl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extrinsic component of cytoplasmic side of plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | non-membrane spanning protein tyrosine kinase activity | |
Molecular Function | signaling receptor binding | |
Biological Process | B cell receptor signaling pathway | |
Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | |
Biological Process | innate immune response | |
Biological Process | T cell differentiation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTyrosine-protein kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Picathartidae > Picathartes
Accessions
- Primary accessionA0A851BHA0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 31-59 | Disordered | ||||
Sequence: SKRQRPIRNGSEVRDPLVSYEPSSPPRSP | ||||||
Domain | 60-120 | SH3 | ||||
Sequence: MQDKLVVALYNYEPKHDGDLGLRKGEKLRVLEENGEWWKAQSLTTGQEGLIPHNFVALANS | ||||||
Domain | 126-223 | SH2 | ||||
Sequence: WFFKNISRKDAERQLLASGNTHGSFLIRESETSKGSYSLSVRDLDESQGETVKHYKIRNLDNGGFYISPRVPFGSLRELVQHYTRSSDGLCCRLGKPC | ||||||
Domain | 244-321 | Protein kinase | ||||
Sequence: LKLVEKLGAGQFGEVWMGFYNGHTKVAVKSLKAGSMAPSAFLAEANLMKKLQHPRLVRLYAVVTKEPIYIITEFMEKG |
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length321
- Mass (Da)36,627
- Last updated2021-09-29 v1
- ChecksumD2C3DA03793AA50F
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: M | ||||||
Non-terminal residue | 321 | |||||
Sequence: G |
Keywords
- Technical term