A0A847KRI3 · A0A847KRI3_9ACTO

  • Protein
    K(+)-insensitive pyrophosphate-energized proton pump
  • Gene
    hppA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for site.

TypeIDPosition(s)Description
Site536Determinant of potassium independence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    K(+)-insensitive pyrophosphate-energized proton pump
  • EC number
  • Alternative names
    • Membrane-bound proton-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (H(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      GX427_10855

Organism names

Accessions

  • Primary accession
    A0A847KRI3

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane38-60Helical
Transmembrane90-108Helical
Transmembrane114-139Helical
Transmembrane183-205Helical
Transmembrane293-316Helical
Transmembrane337-360Helical
Transmembrane372-394Helical
Transmembrane415-446Helical
Transmembrane452-470Helical
Transmembrane542-567Helical
Transmembrane579-599Helical
Transmembrane645-662Helical
Transmembrane668-688Helical
Transmembrane730-751Helical
Transmembrane757-778Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region796-842Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    842
  • Mass (Da)
    89,201
  • Last updated
    2021-09-29 v1
  • Checksum
    04B1A711BF2E6B9F
MTHPWLAPVGALPSASEADLELPDLATVSVLGLSGRTLLALGLVVCVGGLLFGLASYLEISRLPVHRTMREVSELIYSTCKAYLVQQGRFLLVLWAFIAAVIIVYFKFLVGYSWARMAIIVGFSLVGMAGSYAVAWYGIRINTFANSRTAFASLRGRPLPLHAIPMKSGMSIGMVLISIELTIMLLILLVVPPSLAGACFIGFAIGESLGASALRIAGGIFTKIADIGSDLMKIVFHIKEDDARNPGVIADCTGDNAGDSVGPSADGFETYGVTGVALVTFVVLAVPEPAVQATLLVWIFVVRAVMVVASGLSYLANASATRARYGHADRMDFEKPLTTLVWITSAVSIVATYATTWALLGQGATADHWWKLATIISLGTVAGALIPELVKAFTSTKSRHVHEVVKSSRQGGPSLNILSGLVAGNFSAFWLGGAIIVLMAGAYLISEMGLDSLMIAPAVFAFGLVAFGFLSMGPVTIAVDSYGPVTDNAQSVYELSTIEEVPGIDEELRRDHGFEVQWEKAKLMLEENDGAGNTFKATAKPVLIGTAVVGATTMIFSIIVALTGGLTTGLENLSLLHPPFLLGLVTGGAVIFWFTGASIQAVTTGSYRAVEFIRDNIRLDGVTKASEQDSRRVVEICTQYAQRGMLNMFLGVFFATLAFAFIEPFFFVGYLISIAVFGLYQAIFMANAGGAWDNAKKIVETDLHAKGTALHDATIVGDTVGDPYKDTSSVALNPVIKFTTLFGLLAVELAVNLTNQGFGTLVLVLAGAFLAVTCYFVYRSFYGMRIATTLDDDEDAVLPPSGDGGHDAGVSPVPLDTGVDGRIRGVPAVAPAQPVLSGRNPR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAYUO010000184
EMBL· GenBank· DDBJ
NLI19288.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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