A0A843J8Z7 · A0A843J8Z7_9EURY
- Proteintryptophan synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids453 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
Catalytic activity
- (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan
Cofactor
Pathway
Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity | |
Molecular Function | pyridoxal phosphate binding | |
Molecular Function | tryptophan synthase activity |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametryptophan synthase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanomicrobiales > Methanomicrobiaceae > Methanomicrobium
Accessions
- Primary accessionA0A843J8Z7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Tetramer of two alpha and two beta chains.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 77-414 | Tryptophan synthase beta chain-like PALP | ||||
Sequence: YRPSPLVRAYCLEEALDTPAKIYYKFEGNNTSGSHKLNSAIAQAYYAKKQGLKGVTTETGAGQWGTALSMACAYLNLDCKVFMVKVSYEQKPFRREVMRTYGASVVPSPSEATDVGKKILAEHPGTTGSLGCAISEAVEVAVKNPGYRYVLGSVLNQVLLHQSIIGLETKTALDKYDIKPDIIIGCAGGGSNLGGLIAPFMREKLRGEADYRIIAVEPASCPSFTRGTFAYDFADTGMICPLAKMYTLGSSFIPSANHAGGLRFHGMSTILSQLYHDGYMEAVAVEQTSVFEAAVQFARTEGILPAPESSHAIRTAIDEALKCKKTGEEKNIVFGLTG |
Family and domain databases
Sequence
- Sequence statusComplete
- Length453
- Mass (Da)49,603
- Last updated2021-09-29 v1
- Checksum16E9D13C2EF20072