A0A840DM18 · A0A840DM18_9BACI
- ProteinUDP-N-acetylmuramoylalanine--D-glutamate ligase
- GenemurD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids451 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
Catalytic activity
- UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + ADP + phosphate + H+
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UDP-N-acetylmuramoylalanine-D-glutamate ligase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylmuramoylalanine--D-glutamate ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Anoxybacillus
Accessions
- Primary accessionA0A840DM18
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 117-291 | Mur ligase central | ||||
Sequence: ITGSNGKTTTTTLIYEMLKEGKKQPLIAGNIGAVACEVAQTAAEDNWIVTELSSFQLMGIQTFRPHIAVLLNLFDAHLDYHGTKEAYAQAKGNLFKNQTESDYAVVNADDEWVRKLADLSQAKKIWFSATTPLSSGAYVCENALYWDEEKIINLSDIALPGKHNVENILAALSVA | ||||||
Domain | 313-427 | Mur ligase C-terminal | ||||
Sequence: HRLQYVGTVAGRKFFNDSKATNILATQKALAAFTSQPVILLAGGLDRGNEFDALIPYLRHVKAIVLFGQTAPKLERVAKEAGIETICHVDNVEKAVPVAYELSAPGDVILLSPAC |
Sequence similarities
Belongs to the MurCDEF family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length451
- Mass (Da)49,130
- Last updated2021-09-29 v1
- ChecksumA9F7C5F88EFA13EB