A0A836XKE2 · A0A836XKE2_9GAMM

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mg2+ or Mn2+ ion per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site105NADP+ (UniProtKB | ChEBI)
Binding site114substrate
Binding site116substrate
Binding site120substrate
Binding site130substrate
Binding site154substrate
Site161Critical for catalysis
Site231Critical for catalysis
Binding site308Mg2+ (UniProtKB | ChEBI)
Binding site340-346NADP+ (UniProtKB | ChEBI)
Binding site353NADP+ (UniProtKB | ChEBI)
Binding site392NADP+ (UniProtKB | ChEBI)
Binding site396NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionisocitrate dehydrogenase (NADP+) activity
Molecular Functionmagnesium ion binding
Molecular FunctionNAD binding
Biological Processglyoxylate cycle
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isocitrate dehydrogenase [NADP]
  • EC number

Gene names

    • ORF names
      EYQ44_02605

Organism names

Accessions

  • Primary accession
    A0A836XKE2

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue101N6-succinyllysine
Modified residue114Phosphoserine
Modified residue143N6-acetyllysine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain30-413Isopropylmalate dehydrogenase-like

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    417
  • Mass (Da)
    45,546
  • Last updated
    2021-09-29 v1
  • Checksum
    D248A64B519D2C2B
MGYKYIQVPASGEKITVNADFSINVPNNPIIPFIEGDGIGIDITPVMVKVIDAAVAKAYDGQKKISWMEVFCGEKAAELYEGDWFPAETLEAVKEYIVSIKGPLTTPVGGGFRSLNVALRQELDLFVCQRPVRWFSGVPSPVKEPNKVDMCIFRENSEDIYAGIEWKAGSDEATKVIKFLQDEMKVTKIRFDTNCGIGVKPVSEEGTKRLVTKAIQYAIDQNKPSVTLVHKGNIMKFTEGAFCDWGYEVARESFGGEPLDGGPWHTVKNPNTGEDIVIKDVIADAMLQQIILRPDEYSVLATLNLNGDYISDALAAQVGGIGIAPGANLSDDIAIFEATHGTAPKYAGQDKVNPGSLILSAEMMLRHLGWGDAADLVIKGIEGAITEKKVTYDFERLMDDAILMSCSEFGDAMIENM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DUBX01000023
EMBL· GenBank· DDBJ
HIG66709.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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