A0A800GHQ0 · A0A800GHQ0_9GAMM

  • Protein
    Bifunctional purine biosynthesis protein PurH
  • Gene
    purH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.
Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionIMP cyclohydrolase activity
Molecular Functionphosphoribosylaminoimidazolecarboxamide formyltransferase activity
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional purine biosynthesis protein PurH

Including 2 domains:

  • Recommended name
    Phosphoribosylaminoimidazolecarboxamide formyltransferase
  • EC number
  • Alternative names
    • AICAR transformylase
  • Recommended name
    IMP cyclohydrolase
  • EC number
  • Alternative names
    • ATIC
    • IMP synthase
    • Inosinicase

Gene names

    • Name
      purH
    • ORF names
      EYQ57_02465

Organism names

  • Taxonomic identifier
  • Strain
    • UWMA-0327
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Methylococcales > Methylococcaceae

Accessions

  • Primary accession
    A0A800GHQ0

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-146MGS-like

Domain

The IMP cyclohydrolase activity resides in the N-terminal region.

Sequence similarities

Belongs to the PurH family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    519
  • Mass (Da)
    56,004
  • Last updated
    2021-06-02 v1
  • Checksum
    4072052E5AB2B117
MNKKIARALISVSDKSNILEFCQQLQQLGVELLSTGGTAKLLADNAIPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGIDDEIMAANDIKAIDLVVVNLYPFEQTIANPDCDLATAIENIDIGGPTMIRAAAKNHKDVTVVVDPNDYSTIIDELNSNAVSICQQSRFDLALKSFEHTARYDTAISAYLGAVNEVQFPATLNLQFHHTQSMRYGENPHQNAAFYIENNPASGSIAAATQIQGKALSYNNIADADAALECVKSFSEQPTCVIVKHANPCGVAQAENILSAYDLAYATDPTSAFGGIIAFNQVLDEATAAEIIKRQFVEVIIAPEISAKAKTLLAEKKNVRVLECGTWDKHNSAAFDYKRVSSGLLVQDKDLGEITLQDLKVVSQRQPSEQQMNDMLFAWKVAKFVKSNAIVYCKNGQTIGVGAGQMSRVYSAKVAGIKAADEGLIVSGSAMASDAFFPFRDGIDAAAEAGITAVIQPGGSMRDPEVIAAADEHNIAMVFTGMRHFRH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DUCK01000070
EMBL· GenBank· DDBJ
HIF54044.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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