A0A7Y5N8R8 · A0A7Y5N8R8_9MICO

Function

function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site10-17NADP+ (UniProtKB | ChEBI)
Binding site141NADP+ (UniProtKB | ChEBI)
Binding site171substrate
Binding site175substrate
Binding site209substrate
Binding site228substrate
Active site233Proton acceptor
Binding site319substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number
  • Short names
    G6PD

Gene names

    • Name
      zwf
    • ORF names
      HOQ27_11915

Organism names

Accessions

  • Primary accession
    A0A7Y5N8R8

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-180Glucose-6-phosphate dehydrogenase NAD-binding
Domain182-458Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    477
  • Mass (Da)
    53,683
  • Last updated
    2021-06-02 v1
  • Checksum
    15ACFF41B9EED735
MPATTVVLFGATGDLARRKLLPGMLHLHESQLLEGLRVVATSLDELSRDQFLDLAFTAIREHSSHDVTDDDLREFAERIHWVPGSAGPQGIRDAVDESEAILGPDAWRLHYLSVPPKAALAVVHQLEEAKLVERSRIIMEKPFGTDLESAKALNAELHQVFDEEQIFRIDHFLGKEAAQNILAFRFANGLFEPIWHRNHIDHIQIDVPETLGLAQRADFYEGTGAYRDMVVTHLFQVLAFTAMEPPTALEPHAISEEKNKVFRSMAPIEPHNVVRGQYVGYRDVAGVAPESQTETFVALKCFVDNWRWAGVPFFLRTGKRMAEGARIISIAFKEPPRSMFPASSGVGDNGPDHLTFDLADKARMSLSFYGKRPGPGMKLDKLSMQFSMQETNWAGAVLEAYERLIYDAARGDRTLFTSAEGIERLWEVSQPLLDNPPVVRPYEPGTWGPNQIHQLVAPFTWRLPFERRWRDPNASGS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABFYD010000449
EMBL· GenBank· DDBJ
NUO35752.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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