A0A7Y3VCQ2 · A0A7Y3VCQ2_9VIBR

  • Protein
    Biosynthetic arginine decarboxylase
  • Gene
    speA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site300-310substrate
Active site521Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • ORF names
      FKN05_09995

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 1-1(7)
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio

Accessions

  • Primary accession
    A0A7Y3VCQ2

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue115N6-(pyridoxal phosphate)lysine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain96-360Orn/DAP/Arg decarboxylase 2 N-terminal
Domain384-471Arginine decarboxylase helical bundle
Domain599-647Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    650
  • Mass (Da)
    73,633
  • Last updated
    2021-06-02 v1
  • Checksum
    3CED96D415C2D646
MSRHYILFVFVRYQVEKSSKLDRVRADYNVHYWSQGFYGINDQGEVYVSPRKDRAYSTALSSIVQQLEARNLNLPVLVRFPQILHQRVHNICDAFNQAIEECDYPNQYLLVYPIKVNQQKEVVDEILASQAKLETKQLGLEAGSKPELLAVLAMAQQASSVIVCNGYKDREYIRLALIGEKLGHKVFIVLEKLSELELVLKEAKSLGVQPRLGLRIRLASQGAGKWQSSGGEKSKFGLAAAQVLTVIERLKVEQQLDTLQLVHFHLGSQMANIRDVRNGVNEAARFYCELRELGAQIDYFDVGGGLAVDYDGTRSQSSNSMNYGLQEYARNIVSVVADMCTLYQQPKPIIISESGRSITAHHAVLITNVIGTEIYSPETISEPDADAPLLMQNMWRSWETLREGTDARALIEIYNDTQSDLSEAHTLFASGVINLPHRAWIEQLSLRIYHELRLKMSTKNRFHRPILDELQERLADKFFVNFSLFQSLPDAWGIDQVFPVLPLSGLEHVDDRRAVMLDITCDSDGAIEQYVEGQGIETTLPVPAWSKDTPYLMGFFLVGAYQEILGDMHNLFGDTHSVVVHINDQGESEITFINEGDTVEDMMRYVHIDVDAIRANYRQLVSQRVAEQEQATVLEELEQGLSGYTYLEDF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VHSP01000002
EMBL· GenBank· DDBJ
NNN45005.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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