A0A7X6BMM0 · A0A7X6BMM0_9CAUL
- ProteinHistidine--tRNA ligase
- GenehisS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids501 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 92-94 | L-histidine (UniProtKB | ChEBI) | ||||
Sequence: DLT | ||||||
Binding site | 122 | L-histidine (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 136 | L-histidine (UniProtKB | ChEBI) | ||||
Sequence: Q | ||||||
Binding site | 140 | L-histidine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 306 | L-histidine (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 310-311 | L-histidine (UniProtKB | ChEBI) | ||||
Sequence: YY |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | histidine-tRNA ligase activity | |
Biological Process | histidyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHistidine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Caulobacterales > Caulobacteraceae > Brevundimonas
Accessions
- Primary accessionA0A7X6BMM0
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 39-385 | Aminoacyl-transfer RNA synthetases class-II family profile | ||||
Sequence: ERWGFEPLDTGAFEYADALGKFLPDADRPNEGVFALQDDPDEEGNGEWMALRYDLTAPLARFAAQNWETLPKPFRRYAFGPVWRNEKPGPGRFREFVQCDADTVGSDRPEADAEIIAMACEGLQSAGLASDQAVIRVSNRKLFDGLFEAGGVEDAGQKLTALRAIDKYDRLGWEGVVALLGEGRLDESGDYTKGAQLPPKVIAAIEGFLASANSSDLSRADTLKAVSLSGSIGVIGESALNELAAIDAALNAMKVDQASVRFDPTIVRGLEYYTGAVFEAELLLETTDDKGRAVRFGSIGGGGRYDDLVARFTGERLPATGFSFGVSRLASALRAAGRGGEDAVRGP |
Sequence similarities
Belongs to the class-II aminoacyl-tRNA synthetase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length501
- Mass (Da)53,658
- Last updated2021-06-02 v1
- Checksum85D8AECACD4678FC