A0A7S9GFM6 · A0A7S9GFM6_9TELE

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespirasome
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological Processmitochondrial electron transport, NADH to ubiquinone

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 2
  • EC number

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strain
    • Elau1
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Leuciscidae > Pogonichthyinae > Exoglossum

Accessions

  • Primary accession
    A0A7S9GFM6

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane24-44Helical
Transmembrane56-79Helical
Transmembrane142-160Helical
Transmembrane166-183Helical
Transmembrane203-221Helical
Transmembrane241-258Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-252NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain254-296NADH dehydrogenase subunit 2 C-terminal

Sequence similarities

Belongs to the complex I subunit 2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    296
  • Mass (Da)
    32,185
  • Last updated
    2021-06-02 v1
  • Checksum
    5B7AB5BCBFFA8D0C
TLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWVTGEWDMNNMSNPIASAMIMTALALKIGLAPMHFWMPEVLQGLDLPTGLILSTWQKLAPLALIIQTAQAIDPLLLTTLGLTSTLVGGWGGLNQTQLRKILAYSSIAHMGWMIIVLQYAPQLTLLALLTYIFMTSAAFLTLKVSSTTKIGTLATIWSKSPILTATTALVLLSLGGLPPLTGFMPKWLILQELAKQDLPLIATMMAIAALLSLYFYLRLCYAMTLTISPNTTASTTPWRIQTSRPSLPLALFTVM

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue296

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN996915
EMBL· GenBank· DDBJ
QPF70693.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp