A0A7M1CFN8 · A0A7M1CFN8_9ROSI
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- GeneaccD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids492 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- acetyl-CoA + N6-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N6-biotinyl-L-lysyl-[protein]
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Cellular Component | plastid | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Encoded on
- Plastid
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Sapindales > Rutaceae > Aurantioideae > Citrus
Accessions
- Primary accessionA0A7M1CFN8
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Structure
Family & Domains
Features
Showing features for region, domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 198-219 | Disordered | ||||
Sequence: STNGSDLTISESSNESESSNES | ||||||
Domain | 228-492 | CoA carboxyltransferase N-terminal | ||||
Sequence: LWVQCENCYGLNYKKFLKSKMYLCEQCGYHLKMISSDRIDLLVDPGTWDPMDDDMVSIDPIEFDSEEEPYKNRIDSYQSKTGLTEAVQTGTGQLNGIPIAIGVMDFQFMGGSMGSVVGEKITRLIEYAANKFLPLLLVCASGGARMQEGSLSLMQMAKISSALYDYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQEAEYLFDKGLFDPIVPRNPLKGVLSELFLFHGRFPLNQN | ||||||
Zinc finger | 232-254 | C4-type | ||||
Sequence: CENCYGLNYKKFLKSKMYLCEQC |
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length492
- Mass (Da)55,372
- Last updated2021-04-07 v1
- Checksum6843C74405E09174