A0A7L2WYL9 · A0A7L2WYL9_PANHA

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site108L-glutamate (UniProtKB | ChEBI)
Active site385Nucleophile
Binding site403-405L-glutamate (UniProtKB | ChEBI)
Binding site427L-glutamate (UniProtKB | ChEBI)
Binding site489L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionacyltransferase activity
Molecular Functionglutathione hydrolase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • Name
      Ggt5
    • ORF names
      PANHAL_R10294

Organism names

  • Taxonomic identifier
  • Strain
    • B10K-DU-012-58
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Accipitriformes > Pandionidae > Pandion

Accessions

  • Primary accession
    A0A7L2WYL9

Proteomes

Subcellular Location

Membrane
; Single-pass type II membrane protein

Family & Domains

Sequence similarities

Belongs to the gamma-glutamyltransferase family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    582
  • Mass (Da)
    62,779
  • Last updated
    2021-04-07 v1
  • Checksum
    2F1CFE5AAFD45FAA
LDMSTGKICCLVLLTLGVLAVVVALVVILTQPKCGPQRYLHGAVAADTETCSVIGRDILKSGGTAVDAAIAGLICTSVMNPQSSGLGGGVVFTIYNASTGTVEVINARETVPREFPQNLLSHCKGIPIGSLWIAVPGELRGYEEAHKRYGRLPWKALFEPTIKLLSEPLVISLVMDKIMNHSDFSKPGKSLCPLICDGQRFLKHGEPFRWPALQQTLKAVAENGATAFYEGQIGKALVEDIRKAGSNISLEDLQAYKAEVSPALNITLNNHTTVFSPGPPMGGAVLMFILKILEEYKLHEASLATPAEKVETYHRIAEALKFGNMLKPHMSDPAFSEAQVTVGNMLSDKIAELVRHRIDTRGDHPLNHYNFLESIYNHSYKSKGTSHISVLAADGSAVSATSTINYPFGSFVYSNQTGIILNNELADFCIANRSIKPDKLVCLSCLLNSYIGGIILSASALGEKPPSAMVPSILISKTGDMLVIGGAGGSRIISATAMAIINKLWFGYDLEHAISAPIMHTEGASILFEEHFSEEIRRSLLRRGHKEKSNTLAMNVVQGISKEGKCISAYSDKRKLGKSAGY

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue582

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VYZV01041722
EMBL· GenBank· DDBJ
NXS75912.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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