A0A7L1NUS2 · A0A7L1NUS2_RHICY

Function

function

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

136850100150200250300350
TypeIDPosition(s)Description
Binding site112-116ATP (UniProtKB | ChEBI)
Binding site175ATP (UniProtKB | ChEBI)
Binding site220ATP (UniProtKB | ChEBI)
Binding site276-280ATP (UniProtKB | ChEBI)
Binding site304-309ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionATP binding
Molecular Functioncreatine kinase activity
Biological Processphosphocreatine biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Creatine kinase U-type, mitochondrial
  • EC number
  • Alternative names
    • Acidic-type mitochondrial creatine kinase
    • Ubiquitous mitochondrial creatine kinase

Gene names

    • Name
      Ckmt1
    • ORF names
      RHICYA_R01839

Organism names

  • Taxonomic identifier
  • Strain
    • B10K-DU-002-35
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Coraciimorphae > Bucerotiformes > Rhinopomastidae > Rhinopomastus

Accessions

  • Primary accession
    A0A7L1NUS2

Proteomes

Subcellular Location

Mitochondrion inner membrane
; Peripheral membrane protein

Keywords

Interaction

Subunit

Exists as an octamer composed of four MTCK homodimers.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-82Phosphagen kinase N-terminal
Domain109-351Phosphagen kinase C-terminal

Sequence similarities

Belongs to the ATP:guanido phosphotransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    368
  • Mass (Da)
    42,061
  • Last updated
    2021-04-07 v1
  • Checksum
    0826AE87F3A09D1E
SAEYPDLRKHNNCMASSLTPAIYARLCDKATPNGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQDRHNGYNPRIMKHITDLDHTKIKFGHFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVEKVAVEALNSLTGDLAGRYYRLSEMTEKEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKTFLIWINEEDHTRIISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGNIFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLEKGQDIRIPSPVPQFRH

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue368

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VXBP01009149
EMBL· GenBank· DDBJ
NXO03230.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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