A0A7K6V9I2 · A0A7K6V9I2_9PASS

  • Protein
    Histamine H1 receptor
  • Gene
    Hrh1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionhistamine receptor activity
Biological Processpositive regulation of vasoconstriction
Biological Processregulation of vascular permeability

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Histamine H1 receptor

Gene names

    • Name
      Hrh1
    • ORF names
      NOTCIN_R03940

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • B10K-DU-029-75
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Notiomystidae > Notiomystis

Accessions

  • Primary accession
    A0A7K6V9I2

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane15-39Helical
Transmembrane51-76Helical
Transmembrane82-110Helical
Transmembrane131-155Helical
Transmembrane175-198Helical
Transmembrane399-419Helical
Transmembrane431-453Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain31-450G-protein coupled receptors family 1 profile
Region213-276Disordered
Compositional bias249-263Polar residues
Region299-361Disordered
Compositional bias301-319Basic and acidic residues
Compositional bias320-343Polar residues

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Keywords

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Fragment
  • Length
    468
  • Mass (Da)
    52,738
  • Last updated
    2021-04-07 v1
  • Checksum
    9EF6DDB5B5A5665E
MSKNATESSNTVPSALLGLFLGSISLVTIIMNILVLCAVKAEKKLQTVGNLYIVSLSIADLIVGAAVMPLNIVYLLRPQWPLGLAACLFWLSMDYVASTASIFNLFILCMDRYRSVQQPLKYLKYRTKMRASLMILAVWLLSFTWVIPILGWHVFANNGQRKVKESKCETEFAKVTWFKVLTAILNFYLPSLLMLWFYCRIFRTVREHCQHRELPSGSSWPSLEKNTGHQAKTKDEKNICLQKQILGENAPGTDKQSSPEPQRAEAELNVGTPDTASGALSNGQVLKCSCFSLTTAKPEPGLDKAGRKAPKKPGNKERPGSQDSDSSVASDNHTFTEVTPRAEQPSANPKGACCPQGKTEHRDSRGLRFLRKTWNTLHSHSRRSIHRHGNRERKAAKQLGVIMAAFMLCWIPYFVFFMVTTFHDPEQLSTLHMVTIWLGYVNSTLNPFLYPLCNQNFKKTFRKILHIP

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias249-263Polar residues
Compositional bias301-319Basic and acidic residues
Compositional bias320-343Polar residues
Non-terminal residue468

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VZRX01011852
EMBL· GenBank· DDBJ
NWX31717.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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